Abstract
Adriamycin (synonym doxorubicin) is a glycoside antibiotic whose structure and stereochemistry are represented in Fig. 1 (formula I). It consists of the tetracyclic quinoid aglycone adriamycinone (14-hydroxydaunomycinone) linked to the amino- sugar daunosamine. The chemical name for adriamycin is therefore the following: (7S : 9S)-9-hydroxyacetyl-4-methoxy-7,8,9,10-tetrahydro-6,7,9, ll-tetrahydroxy-7-0- (2′3′6′-trideoxy-3′-amino-α-L-lyxohexopyranosyl)-5,12-naphthacenedione.
1 The trademark of Farmitalia for adriamycin is Adriblastina.
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Arcamone, F. et al. (1972). Structure and Physicochemical Properties of Adriamycin (Doxorubicin). In: Carter, S.K., Marco, A.D., Ghione, M., Krakoff, I.H., Mathé, G. (eds) International Symposium on Adriamycin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-95227-2_2
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