Abstract
Mice. Asymptomatic or mildly affected mice usually have no gross pulmonary changes other than increased lung weights, although a few mildly affected mice have white lines along the course of bronchi, white foci in lymph nodes, and dual lobes of consolidation. Average increases of 50% have been reported by the 5th day and 100% by the 14th day after experimental infection of Swiss mice (Robinson et al. 1968). Overtly ill and genetically susceptible mice have more dramatic increases in lung weights (200%–300%) (Parker et al. 1978). In these cases, one or more lung lobes are plum-colored or contain sharply demarcated plum-colored foci which exude frothy sanguinous fluid when cut. If these mice survive into the 3rd week, consolidated foci are gray.
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Brownstein, D.G. (1985). Sendai Virus Infection, Lung, Mouse and Rat. In: Jones, T.C., Mohr, U., Hunt, R.D. (eds) Respiratory System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-96846-4_32
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