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Creutzfeldt-Jakob Disease

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Magnetic Resonance of Myelin, Myelination, and Myelin Disorders

Abstract

Creutzfeldt-Jakob disease (CJD) is also called subacute spongiform encephalopathy. CJD is a rare transmissible disorder of the CNS which usually becomes manifest in middle-age or the presenile period and ends in death, in many cases within 3–12 months of onset. The disease affects both sexes equally and may be familial. It has been recorded in most parts of the world.

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References

  • Bockman JM, Kingsbury DT, McKinley MP, Bendheim PE, et al. (1985) Creutzfeldt-Jakob disease prion proteins in human brains. N Engl J Med 312: 73–78

    Article  PubMed  CAS  Google Scholar 

  • Bots GTHAM, Man de JCH, Verjaal A (1971) Virus-like particles in brain tissue from two patients with CreutzfeldtJakob disease. Acta Neuropathol 18: 267–270

    Article  PubMed  CAS  Google Scholar 

  • Brown P, Coker-Vann M, Pomeroy K, Franko M, et al. (1986) Diagnosis of Creutzfeldt-Jakob disease by western blot identification of marker protein in human brain tissue. N Engl J Med 314: 547–551

    Article  PubMed  CAS  Google Scholar 

  • Chou SM, Martin JD (1971) Kuru-plaques in a case of Creutzfeldt-Jakob disease. Acta Neuropathol 17: 150–155

    Article  PubMed  CAS  Google Scholar 

  • Cruz-Sanchez F, Lafuente J, Gertz HJ, Stoltenburg-Didinger G (1987) Spongiform encephalopathy with extensive involvement of white matter. J Neurol Sci 82: 81–87

    Article  PubMed  CAS  Google Scholar 

  • Diringer H, Gelderblom H, Hilmert H, Ozel M, et al. (1983) Scrapie infectivity, fibrils and low molecular weight protein. Nature 306: 476–478

    Article  PubMed  CAS  Google Scholar 

  • Field EJ, Narang HK (1972) An electron-microscopic study of scrapie in the rat: Further observations on “Inclusion Bodies” and virus-like particles. J Neurol Sci 17: 347–364

    Google Scholar 

  • Fields BN (1987) Powerful prions? N Engl J Med 317: 1597–1598

    Article  PubMed  CAS  Google Scholar 

  • Harrington MG, Merril CR, Asher DM, Gajdusek DC (1986) Abnormal proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. N Engl J Med 315: 279–282

    Article  PubMed  CAS  Google Scholar 

  • Macchi G, Abbamöndi AL, Di Trapani G, Sbriccoli A (1984) On the white matter lesions of the Creutzfeldt-Jakob disease. J Neurol Sci 63: 197–206

    Article  PubMed  CAS  Google Scholar 

  • Manuelidis L (1985) Creutzfeldt-Jakob disease prion proteins in human brains. N Engl J Med 312: 1643–1644

    PubMed  CAS  Google Scholar 

  • Masters CL, Harris JO, Gajdusek DC, Gibbs CJ, et al. (1979) Creutzfeldt-Jakob disease: Patterns of worldwide occurrence and the significance of familial and sporadic clustering. Ann Neurol 5: 177–188

    Google Scholar 

  • Merz PA, Somerville RA, Wisniewski HM, Iqbal K (1981) Abnormal fibrils from scrapie-infected brain. Acta Neuropathol 54: 63–74

    Article  PubMed  CAS  Google Scholar 

  • Merz PA, Somerville RA, Wisniewski HM, Manuelidis L, et al. (1983) Scrapie-associated fibrils in Creutzfeldt-Jakob disease. Nature 306: 474–476

    Article  PubMed  CAS  Google Scholar 

  • Mizutani T, Okumura A, Oda M, Shiraki H (1981) Panencephalopathic type of Creutzfeldt-Jakob disease: Primary involvement of the cerebral white matter. J Neurol Neurosurg Psychiatry 44: 103–115

    Google Scholar 

  • Monreal J, Collins GH, Masters CL, Fisher CM, et al. (1981) Creutzfeldt-Jakob disease in an adolescent. J Neurol Sci 52: 341–350

    Article  PubMed  CAS  Google Scholar 

  • Park TS, Kleinman GM, Richardson EP (1980) CreutzfeldtJakob disease with extensive degeneration of white matter. Acta Neuropathol 52: 239–242

    Article  PubMed  CAS  Google Scholar 

  • Prusiner SB (1987) Prions and neurodegenerative diseases. N Engl J Med 317: 1571–1581

    Article  PubMed  CAS  Google Scholar 

  • Ridley RM, Baker HF, Crow TJ (1985) Virogenes in scrapie and Creutzfeldt-Jakob disease. J R Soc Med 78: 970

    PubMed  CAS  Google Scholar 

  • Roberts GW, Brown R, Crow TJ, Barry RA, et al. (1986) Prion-protein immunoreactivity in human transmissible dementias. N Engl J Med 315: 1231–1232

    CAS  Google Scholar 

  • Roos R, Gajdusek DC, Gibbs CJ (1973) The clinical characteristics of transmissible Creutzfeldt-Jakob disease. Brain 96: 1–20

    Article  PubMed  CAS  Google Scholar 

  • Rossum van A (1968) Spastic pseudosclerosis. In: Vinken PJ, Bruyn GW, eds. Handbook of clinical neurology, vol 6. Amsterdam: North Holland Publishing Company: 726–760

    Google Scholar 

  • Tateishi J, Nagara H, Hikita K, Sato Y (1984) Amyloid plaques in the brains of mice with Creutzfeldt-Jakob disease. Ann Neurol 15: 278–280

    Article  PubMed  CAS  Google Scholar 

  • Tateishi J, Ohta M, Kuroiwa Y (1978) Subacute spongiform encephalopathy with Kuru plaques and its successful transmission to the small rodents. J Neuropathol Exp Neurol 37: 699

    Article  Google Scholar 

  • Tateishi J, Ohta M, Koga M, Sato Y, et al. (1979) Transmission of chronic spongiform encephalopathy with kuru plaques from humans to small rodents. Ann Neurol 5: 581–584

    Article  PubMed  CAS  Google Scholar 

  • Tomlinson BE, Corsellis JAN (1984) Ageing and the dementias. In: Hume Adams J, Corsellis JAN, Duchen LW, eds. Greenfield’s Neuropathology, 4th ed. London: Edward Arnold: 951–1025

    Google Scholar 

  • Vernon ML, Horta-Barbosa L, Fuccillo DA, Sever JL, et al. (1970) Virus-like particles and nucleo-protein-type filaments in brain tissue from two patients with CreutzfeldtJakob disease. Lancet I: 964–966

    Google Scholar 

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Authors and Affiliations

  1. Department of Diagnostic Radiology and Neuroradiology, Free University Hospital, De Boelelaan 1117, NL-1007 MB, Amsterdam, The Netherlands

    Professor Dr. Jacob Valk

  2. Department of Child Neurology, Academic Hospital, Catharijnesingel 101, NL-3511 GV, Utrecht, The Netherlands

    Dr. Marjo S. van der Knaap

Authors
  1. Professor Dr. Jacob Valk
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  2. Dr. Marjo S. van der Knaap
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© 1989 Springer-Verlag Berlin Heidelberg

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Valk, J., van der Knaap, M.S. (1989). Creutzfeldt-Jakob Disease. In: Magnetic Resonance of Myelin, Myelination, and Myelin Disorders. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-02568-0_38

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  • DOI: https://doi.org/10.1007/978-3-662-02568-0_38

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-02570-3

  • Online ISBN: 978-3-662-02568-0

  • eBook Packages: Springer Book Archive

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