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5-Hydroxytryptamine and Human Heart Function: The Role of 5-HT4 Receptors

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5-HT4 Receptors in the Brain and Periphery

Part of the book series: Biotechnology Intelligence Unit ((BIOIU))

Abstract

5-Hydroxytryptamine (5-HT) can elicit both cardioexcitation and cardiodepression. 5-HT exerts these effects both through a direct action in the heart and indirectly via stimulation of the central nervous system (CNS). Here we concentrate mainly on the direct effects of 5-HT on the heart.

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Authors
  1. Alberto J. Kaumann
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  2. Louise Sanders
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  1. Roche Bioscience, Palo Alto, California, USA

    Richard M. Eglen Ph.D.

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Kaumann, A.J., Sanders, L. (1998). 5-Hydroxytryptamine and Human Heart Function: The Role of 5-HT4 Receptors. In: Eglen, R.M. (eds) 5-HT4 Receptors in the Brain and Periphery. Biotechnology Intelligence Unit. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-05553-3_6

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  • DOI: https://doi.org/10.1007/978-3-662-05553-3_6

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