Zusammenfassung
Kutane Lymphome gehören zur Gruppe der extranodalen Non-Hodgkin-Lymphome, innerhalb derer sie die zweithäufigste Lymphomform darstellen. Die Inzidenz wird auf eine Neuerkrankung pro Jahr und 100000 Einwohner geschätzt [28]. Primäre kutane Lymphome entstehen definitionsgemäß in der Haut und bleiben in der Regel über längere Zeit (mindestens 6 Monate) auf das Hautorgan beschränkt, während sekundäre kutane Lymphome kutane Manifestationen von disseminierten, primär nodalen oder extranodalen Lymphomen darstellen [29]. Primäre kutane Lymphome umfassen ein weites, klinisch und histologisch heterogenes Spektrum lymphoproliferativer Neoplasien, wobei 65% der kutanen Lymphome den kutanen T-Zell-Lymphomen (CTCL), 25% den kutanen B-Zell-Lymphomen (CBCL) und 10% weiteren, seltenen Formen von kutanen Lymphome zugeordnet werden können.
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Literatur
Agnarsson BA, Vonderheid EC, Kadin ME (1990) Cutaneous T cell lymphoma with suppressor/cyto-toxic (CD8) phenotype: identification of rapidly progressive and chronic subtypes. J Am Acad Dermatol 22:569–577
Bauch B, Barraud-Klenowssek M, Burg G, Dummer R (1995) Eindrucksvolle Remission einer Mycosis fungoides im Tumorstadium unter low-dose Interferon-α und Acitretin nach erfolgloser Chemotherapie. Z Hautkr 70:200–203
Bekkenk MW, Geelen FA, van Voorst Vader PC, Heule F, Geerts ML, van Vloten WA, Meijer CJ, Willemze R (2000) Primary and secondary cutaneous CD30(+) lymphoproliferative disorders: a report from the Dutch Cutaneous Lymphoma Group on the long-term follow-up data of 219 patients and guidelines for diagnosis and treatment. Blood 95:3653–3661
Berti E, Tomasini D, Vermeer MH, Meijer CJ, Alessi E, Willemze R (1999) Primary cutaneous CD8-positive epidermotropic cytotoxic T cell lymphomas. A distinct clinicopathological entity with an aggressive clinical behavior. Am J Pathol 155:483–492
Burg G, Hess M, Küng E, Dommann S, Dummer R (1994) Semimalignant („pseudolymphomatous“) cutaneous B-cell lymphomas. Dermatol Clin 12:399–407
Cerroni L, Zochling N, Putz B, Kerl H (1997) Infection by Borrelia burgdorferi and cutaneous B-cell lymphoma. J Cutan Pathol 24:457–461
Chinn DM, Chow S, Kim YH, Hoppe RT (1999) Total skin electron beam therapy with or without adjuvant topical nitrogen mustard or nitrogen mustard alone as initial treatment of T2 and T3 mycosis fungoides. Int J Radiat Oncol Biol Phys 43:951–958
Dummer R, Häffner AC, Hess M, Burg G (1996) A rational approach to the therapy of cutaneous T-cell lymphomas. Onkologie 19:226–230
Dummer R, Willers J, Kamarashev J, Urosevic M, Döbbeling U, Burg G (2000) Pathogenesis of cutaneous lymphomas. Semin Cutan Med Surg 19:78–86
Dummer R, Kamarashev J, Kempf W, Haffner AC, Hess-Schmid M, Burg G (2002) Junctional CD8+ cutaneous lymphomas with nonaggressive clinical behavior: a CD8+ variant of mycosis fungoides? Arch Dermatol 138:199–203
Goldschmidt H, Lukacs S, Schoefìnius HH (1978) Teleroentgen therapy for mycosis fungoides. J Dermatol Surg Oncol 4:600–605
Goldschmidt H (1991) Radiation therapy of other cutaneous tumors. In: Panizzon R (ed) Modern Dermatologic Radiation Therapy. Springer, Berlin, pp 123–132
Grange F, Bekkenk MW, Wechsler J, Meijer CJ, Cerroni L, Bernengo M, Bosq J, Hedelin G, Fink Puches R, van Vloten WA, Joly P, Bagot M, Willemze R (2001) Prognostic factors in primary cutaneous large B-cell lymphomas: a European multi-center study. J Clin Oncol 19:3602–3610
Hoppe RT, Wood GS, Abel EA (1990) Mycosis fun-goides and the Sèzary syndrome: pathology, staging, and treatment. Curr Probi Cancer 14:293–371
Jones GW, Tadros A, Hodson DI, Rosenthal D, Roberts J, Thorson B (1994) Prognosis with newly diagnosed mycosis fungoides after total skin electron radiation of 30 or 35 Gy. Int J Radiat Oncol Biol Phys 28:839–845
Jones GW, Hoppe RT, Glatstein E (1995) Electron beam treatment for cutaneous T-cell lymphoma. Hematol Oncol Clin North Am 9:1057–1076
Jones GW, Wilson LD (1997) Mycosis fungoides and total skin electron beam radiation. Blood 89:3062–3064
Kaye FJ, Bunn PJ, Steinberg SM, Stocker JL, Ihde DC, Fischmann AB, Glatstein EJ, Schechter GP, Phelps RM, Foss FM, Parlette H, Anderson M, Sausville E (1989) A randomized trial comparing combination electron-beam radiation and chemotherapy with topical therapy in the initial treatment of mycosis fungoides. N Engl J Med 321: 1784–1790
Kempf W, Dummer R, Burg G (1999) Approach to lymphoproliferative infiltrates of the skin. The difficult lesions. Am J Clin Pathol 111:84–93
Kim YH, Chow S, Varghese A, Hoppe RT (1999) Clinical characteristics and long-term outcome of patients with generalized patch and/or plaque (T2) mycosis fungoides. Arch Dermatol 135:26–32
Kirova YM, Piedbois Y, Le Bourgeois JP (1999) Radiotherapy in the management of cutaneous B-cell lymphoma. Our experience in 25 cases. Radiother Oncol 52:15–18
Kirova YM, Piedbois Y, Pan Q, Guo L, Le Bourgeois JP (1999) Radiotherapie des lymphomes cutanes. Cancer Radiother 3:105–111
Micaily B, Campbell O, Moser C, Vonderheid EC, Brady LW (1991) Total skin electron beam and total nodal irradiation of cutaneous T-cell lymphoma. Int J Radiat Oncol, Biol, Phys 20:809–813
Savoia P, Fierro MT, Novelli M, Quaglino P, Verrone A, Geuna M, Bernengo MG (1997) CD56-po-sitive cutaneous lymphoma: a poorly recognized entity in the spectrum of primary cutaneous disease. Br J Dermatol 137:966–971
Schirren CG (1955) Roentgen irradiation at a distance using soft radiation at a distance, using soft radiation from beryllium-window tubes. J Invest Dermatol 24:463–467
Vonderheid EC, Bernengo MG, Burg G, Duvic M, Heald P, Laroche L, Olsen E, Pittelkow M, Russell-Jones R, Takigawa M, Willemze R (2002) Update on erythrodermic cutaneous T-cell lymphoma: report of the International Society for Cutaneous Lymphomas. J Am Acad Dermatol 46:95–106
Voss N, Kim Sing C (1998) Radiotherapy in the treatment of dermatologic malignancies. Dermatol Clin 16:313–320
Weinstock MA (1994) Epidemiology of mycosis fungoides. Semin Dermatol 13:154–159
Willemze R, Kerl H, Sterry W, Berti E, Cerroni L, Chimenti S, Diaz Perez JL, Geerts ML, Goos M, Knobler R, Ralfkiaer E, Santucci M, Smith N, Wechsler J, van Vloten WA, Meijer CJ (1997) EORTC classification for primary cutaneous lymphomas: a proposal from the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer. Blood 90:354–371
Wiskemann A, Buck C (1978) Radiotherapy of mycosis fungoides: twenty years of experience with teleroentgen and low-voltage X-ray therapy. J Dermatol Surg Oncol 4:606–610
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Dummer, R., Burg, G. (2003). Strahlentherapie kutaner Lymphome. In: Dummer, R. (eds) Physikalische Therapiemaßnahmen in der Dermatologie. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-662-12704-9_18
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DOI: https://doi.org/10.1007/978-3-662-12704-9_18
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