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Intestinal Epithelial Hyperpermeability

  • Conference paper
Yearbook of Intensive Care and Emergency Medicine 1997

Part of the book series: Yearbook of Intensive Care and Emergency Medicine ((YEARBOOK,volume 1997))

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Abstract

The gut serves not only as a portal of entry for nutrients, small ions, and water, but also as a selective barrier preventing systemic contamination by lumen-derived microbes or microbial products. A key component of the gastrointestinal barrier is the epithelium itself. There are only two ways that substances (ions, molecules, or particles) can traverse the epithelium from the lumenal compartment to the basolateral compartment. Permeation can occur via the transcellular pathway (i.e. through cells) or via the paracellular pathway (i.e. between cells).

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Authors
  1. M. P. Fink
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Editors and Affiliations

  1. Department of Intensive Care, Erasme Hospital, Free University of Brussels, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean-Louis Vincent (Clinical Director) (Clinical Director)

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© 1997 Springer-Verlag Berlin Heidelberg

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Fink, M.P. (1997). Intestinal Epithelial Hyperpermeability. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 1997. Yearbook of Intensive Care and Emergency Medicine, vol 1997. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-13450-4_54

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  • DOI: https://doi.org/10.1007/978-3-662-13450-4_54

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