Abstract
The earliest therapeutic use of artificially produced radioactive isotopes in medicine was in the field of hematology, and dates back to the Summer of 1936 when radiophosphorus was administered to a patient with chronic lymphatic leukemia. This was twenty years ago when radioisotopes first became available for medical investigations from the 37-inch cyclotron in Berkeley (11). Since that time, and especially in recent years with the development of the nuclear reactor and its immense capacity for producing radioactivity, there has been an increasingly widespread use of radioisotopes throughout the world in the study, diagnosis, and treatment of hematological and other diseases.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Berlin, N. F., D. I. Rowles, G. M. Hyde, R. J. Parsons, P. C. Sampson and S. Port: The blood volume and blood turnover in thoracic surgery as determined by P32 labelled red blood cells. Surg etc. 92, 712 (1951).
Berlin, N. I., G. M. Hyde, R. J. Parsons and J. H. Lawrence: The blood volume in various medical and surgical conditions. New Engl. J. Med. 247, 675 (1952).
Berlin, N. F., J. H. Lawrence and H. C. Lee: The pathogenesis of the anemia of chronic leukemia: measurement of the life span of the red blood cell with glycine-2-C14 J. Labor. a. Clin. Med. 44, 860 (1954).
Berlin, N. I., and J. H. Lawrence: Recent advances in methods for the study of red cell mass and red cell production and destruction, to be published in the proceedings of the International Conference on Peaceful Uses of Atomic Energy. Geneva, August 1955.
Dobson, E. L., G. F. Warner, C. R. Finney and M. E. Johnston: The measurement of liver circulation by means of the colloid disappearance rate. I. Liver blood flow in normal young men. Circulation 7, 690 (1953).
Dobson, R. L., and E. L. Dobson: Unpublished data.
Elmlinger, P. J., R. L. Huff, C. A. Tobias and J. H. Lawrence: Iron turnover abnormalities in patient’s having anemia: serial blood and in vivo tissue studies with Fe59. Acta haematol. (Basel) 9, 73 (1953).
Hevesy, G., and K. Zerahn: Determination of the blood red corpuscle content. Acta physiol. scared. (Stockh.) 4, 376 (1942).
Huff, R. L., T. G. Hennessey, R. E. Austin, J. F. Garcia, B. M. Roberts and J. H. Lawrence: Plasma and red cell iron turnover in normal subjects and in patients having various hematopoietic disorders. J. Clin. Invest. 29, 1041 (1950).
Huff, R. L., P J Elmlinger, J. F. Garcia, J. M. Oda, M. C. Cookrey and J. H. Lawrence: Ferrokinetics in normal persons and in patients having various erythropoietic disorders. J. Clin. Invest. 30, 1512 (1951)
Lawrence, J. H.: Nuclear physics and therapy. Preliminary report on a new method for the treatment of leukemia and polycythemia. Radiology 35, 51 (1940).
Lawrence, J. H., R. L. Donsox, B. V. A. Low-Beer and B. R. Brown: Chronic myelogenous leukemia: a study of 129 cases in which treatment was with radioactive phosphorus. J. Amer. Med. Assoc. 136, 672 (1948).
Lawrence, J. H., B. V. A. Low-Beer and J. W. J. Carpender: Chronic lymphatic leukemia: a study of 100 patients treated with radioactive phosphorus. J. Amer. Med. Assoc. 140, 585 (1949).
Lawrence, J. H., P. J. Elmlinger and G. Fulton: Oxygen and the control of red cell production in primary and secondary polycythemia: effects on the iron turn-over patterns with Fe59 as tracer. Cardiologia 21, 337 (1952).
Lawrence, J. H., N. I. Berlin and R. L. Huff: The nature and treatment of polycythemia: studies on 263 patients. Medicine 32, 323 (1953).
Lawrence, J. H.: Radioactive isotopes in hematologic therapy, to be published in the proceedings of the International Conference on Peaceful Uses of Atomic Energy. Geneva, August 1955.
Sterling, K., and S. J. Gray: Determination of the circulating red cell volume in man by radioactive chromium. J. Clin. Invest. 29, 1614 (1950).
Weaver, J. C. and H. Benteen: Unpublished data.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1956 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Dobson, R.L., Lawrence, J.H. (1956). Radioisotopes in Hematology.. In: Begemann, H. (eds) Fünfter Kongress der Europäischen Gesellschaft für Hämatologie, Freiburg i. Br., 20. bis 24. September 1955 / Cinquième Congrès de la Société Européenne d’Hématologie, Freiburg i. Br., Allemagne, 20–24 Septembre 1955. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-35395-0_4
Download citation
DOI: https://doi.org/10.1007/978-3-662-35395-0_4
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-02063-9
Online ISBN: 978-3-662-35395-0
eBook Packages: Springer Book Archive