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Effekte der Adipositaschirurgie auf Hunger und Sättigung

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Psychosoziale Aspekte der Adipositas-Chirurgie

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Zusammenfassung

Hunger und Sättigung werden vorrangig über peptiderge Transmitter vermittelt, die im Gastrointestinaltrakt gebildet werden und über die Darm-Gehirn-Achse ihre Wirkung entfalten. Während eine Vielzahl von anorexigenen (die Nahrungsaufnahme hemmenden) Botenstoffe bekannt ist, gibt es derzeit nur einen bekannten peripher produzierten und zentral wirksamen orexigenen (die Nahrungsaufnahme stimulierenden) Botenstoff. Interessanterweise wird mittlerweile auch das Darm-Mikrobiom als wichtiger Regulator von Hunger und Sättigung gesehen. Das peptiderge Signalmuster ist unter den Bedingungen der Adipositas deutlich verändert. Bariatrische Chirurgie kann einige dieser Veränderungen beeinflussen, dies wird maßgeblich mit dem Erfolg der Methode in Zusammenhang gebracht. Das Kapitel gibt einen Überblick über entsprechende Kompensations- und Adaptationsmechanismen, zeigt aber auch bestehende Lücken in unserem Verständnis zu diesen Regelkreisen auf.

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Authors and Affiliations

  1. Psychosomatische Medizin und Psychotherapie, Universitätsklinikum Tübingen, Tübingen, Deutschland

    Andreas Stengel

  2. Medizinische Klinik m. S. Psychosomatik, Charité – Universitätsmedizin Berlin, Berlin, Deutschland

    Andreas Stengel

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  1. Andreas Stengel
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Correspondence to Andreas Stengel .

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Editors and Affiliations

  1. Klinik für Psychosomatik und Psychotherapie, Medizinische Hochschule Hannover, Hannover, Deutschland

    Martina de Zwaan

  2. Klinik für Psychosomatische Medizin und Psychotherapie, LWL-Universitätsklinikum der Ruhr-Universität Bochum, Bochum, Deutschland

    Stephan Herpertz

  3. Abteilung für Psychosomatische Medizin und Psychotherapie, Medizinische Universitätsklinik Tübingen, Tübingen, Deutschland

    Stephan Zipfel

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Stengel, A., Stengel, A. (2019). Effekte der Adipositaschirurgie auf Hunger und Sättigung. In: de Zwaan, M., Herpertz, S., Zipfel, S. (eds) Psychosoziale Aspekte der Adipositas-Chirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-57364-8_10

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