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Scleroderma

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Autoimmune Diseases of the Skin

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Abstract

Localized scleroderma (LS) or morphea encompasses a group of disorders characterized by limited and localized inflammatory sclerosis (thickening) and fibrosis of the skin, subcutaneous tissue, fascia and/or adjacent muscle. In contrast to systemic sclerosis, Raynaud’s phenomenon, acrosclerosis and internal organ involvement do not usually occur. Morphea may be divided into five subtypes: plaque, generalized, bullous, linear and deep, based on the extent, form and depth of cutaneous sclerosis (Peterson et al. 1995). These subtypes frequently occur together in the same patient. Although morphea is rarely life threatening, significant morbidity and disability occur, particularly in the linear and deep forms.

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Authors
  1. Catherine H. Orteu
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  2. Jan P. Dutz
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  3. Nicolas Hunzelmann
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  4. Thomas Krieg
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Editor information

Editors and Affiliations

  1. Department of Dermatology, University of Erlangen, Hartmannstr. 14, 91052, Erlangen, Germany

    Michael Hertl MD (Professor of Dermatology) (Professor of Dermatology)

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© 2001 Springer-Verlag Wien

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Orteu, C.H., Dutz, J.P., Hunzelmann, N., Krieg, T. (2001). Scleroderma. In: Hertl, M. (eds) Autoimmune Diseases of the Skin. Springer, Vienna. https://doi.org/10.1007/978-3-7091-3704-8_4

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  • DOI: https://doi.org/10.1007/978-3-7091-3704-8_4

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-3706-2

  • Online ISBN: 978-3-7091-3704-8

  • eBook Packages: Springer Book Archive

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