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A Scanning Electron Microscopic (SEM) Study of the Re-Endothelialization of the Carotid End-To-Side Anastomosis in the Rat

  • Conference paper
Proceedings of the 6th European Congress of Neurosurgery

Part of the book series: Acta Neurochirurgica ((NEUROCHIRURGICA,volume 28))

  • 112 Accesses

Summary

A carotid end-to-side anastomosis was made on 25 male Wistar rats (mean weight 197.8 g). At different time intervals, from 0 to 21 days after the operation, the animals were sacrified. The anastomosis was exposed, the aorta was cannulated, and the animals were perfused at a constant pressure of 80 mm Hg with a 2 1/2% glutaraldehyde solution. The anastomoses were taken out for further SEM and light microscopic (LM) study. The SEM results indicate that after the acute platelet-fibrin reaction in the first 48 hours the suture line itself becomes reendothelialized after 4 days. On the stitches, however (EthilonR 11 × 0, 2871 G, BV 7 needle) after two days a cellular population was seen, consisting of leucocytes transforming into flattened cells. The morphology of these cells and their role in the regeneration of endothelium is discussed. This study gives evidence to the possibility of a blood-borne genesis of endothelial cells in vivo.

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Authors and Affiliations

  1. Sophia Hospital, Zwolle, The Netherlands

    P. W. Gelderman

Authors
  1. P. W. Gelderman
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Editor information

Editors and Affiliations

  1. Clinique Neurochirurgicale, Université Libre de Bruxelles, Rue Héger-Bordet, 1, B-1000, Bruxelles, Belgium

    J. Brihaye

  2. Middlesbrough General Hospital, Ayresome Green Lane, TS5 5AZ, Middlesbrough, Cleveland, UK

    P. R. R. Clarke

  3. Neurochirurgische Universitätsklinik, D-6650, Homburg/Saar, Federal Republic of Germany

    F. Loew

  4. Odense University Hospital, DK-5000, Odense, Denmark

    J. Overgaard M.D.

  5. National Institute of Neurosurgery, Amerikai út 57, H-1145, Budapest, Hungary

    E. Pásztor M.D.

  6. Groupe Hospitalier Pitié-Salpêtrière, Université de Paris VI, Clinique Neuro-Chirurgicale, 83, Boulevard de l’Hôpital, F-75013, Paris, France

    B. Pertuiset

  7. Neurochirurgische Klinik, Johannes Gutenberg-Universität, Langenbeckstrasse 1, D-6500, Mainz, Federal Republic of Germany

    K. Schürmann

  8. Consultant Neurosurgeon, Gough Cooper Department of Neurological Surgery, The National Hospital, Queen Square, WC1N 3BG, London, UK

    L. Symon T.D., F.R.C.S.

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© 1979 Springer-Verlag Wien

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Gelderman, P.W. (1979). A Scanning Electron Microscopic (SEM) Study of the Re-Endothelialization of the Carotid End-To-Side Anastomosis in the Rat. In: Brihaye, J., et al. Proceedings of the 6th European Congress of Neurosurgery. Acta Neurochirurgica, vol 28. Springer, Vienna. https://doi.org/10.1007/978-3-7091-4088-8_60

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  • DOI: https://doi.org/10.1007/978-3-7091-4088-8_60

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-4090-1

  • Online ISBN: 978-3-7091-4088-8

  • eBook Packages: Springer Book Archive

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