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Das dopaminerge System und schizophrene Erkrankungen

  • Conference paper
Schizophrenie — Moderne Konzepte zu Diagnostik, Pathogenese und Therapie

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Zusammenfassung

Die Dopamin (DA)-Hypothese der Schizophrenie geht von einer Überaktivität dopaminerger Neurone aus, welche durch eine vermehrte Ausschöttung von DA oder eine öberschieβende Reaktion des DA-Rezeptors bedingt sein kann. Die antipsychotische Wirkung der Neuroleptika auf der Grundlage des DA-Antagonismus ist ein wichtiger Beleg för diese Hypothese. Umgekehrt können unter Anwendung von Substanzen, die zu einer vermehrten DA-Ausschiittung föhren, wie beispielsweise Amphetamin, Psychose-ahnliche Zustande beobachtet werden.

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Author information

Authors and Affiliations

  1. Psychiatrische Klinik und Poliklinik, LMU München, Nußbaumstraße 7, D-80336, München, Bundesrepublik Deutschland

    Dr. med. T. Mager

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  1. Dr. med. T. Mager
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  2. E. M. Meisenzahl
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Editors and Affiliations

  1. Psychiatrische Klinik und Poliklinik, Ludwig-Maximilians-Universität, Nußbaumstraße 7, D-80336, München, Bundesrepublik Deutschland

    Hans-Jürgen Möller  & Norbert Müller  & 

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© 1998 Springer-Verlag Wien

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Mager, T., Meisenzahl, E.M. (1998). Das dopaminerge System und schizophrene Erkrankungen. In: Möller, HJ., Müller, N. (eds) Schizophrenie — Moderne Konzepte zu Diagnostik, Pathogenese und Therapie. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6471-6_8

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  • DOI: https://doi.org/10.1007/978-3-7091-6471-6_8

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-83086-4

  • Online ISBN: 978-3-7091-6471-6

  • eBook Packages: Springer Book Archive

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