Summary
Salivary monoamine oxidase A inhibitory activity (MAO-AI), mean arterial blood pressure (MAP) and heart rate (HR) were determined simultaneously in healthy male students (n = 13) at rest, before a mild psychological stressor, twice during the task and 18 minutes after the end of the task. The sample as a whole showed significant differences in MAP and HR across occasions (respectively, p < 0.001 for both). Salivary MAO-AI could distinguish novice and experienced game players (p < 0.02) and was consistently positively correlated with MAP (r = 0.58, p < 0.05 on occasion 2). Pre-task measures of MAO-AI for an increased sample (n = 18) were associated with higher MAP (but not HR) throughout the experiment (p < 0.05). Those subjects with falling MAO-AI profiles from task to recovery showed significantly greater simultaneous decline in HR than those with a rising MAO-AI profile (p < 0.05).
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References
Carroll D, Ring C, Shrimpton J, Evans P, Gonneke HM, Hucklebridge F (1996) Secretory immunoglobulin A and cardiovascular responses to acute psychological challenge. Int J Behav Med 3: 266–279
Doyle A, Pang F-Y, Bristow M, Hucklebridge F, Evans P, Clow A (1996a) Urinary cortisol and endogenous monoamine oxidase inhibitors(s), but not isatin, are raised in anticipation of stress and/or arousal in normal individuals. Stress Med 12: 43–49
Doyle A, Hucklebridge F, Evans P, Clow A (1996b) Urinary output of endogenous monoamine oxidase inhibitory activity is related to everyday stress. Life Sci 58:1723–1730
Doyle A, Hucklebridge F, Evans P, Clow A (1997) Salivary monoamine oxidase A and B inhibitory activities correlate with stress. Life Sci 59: 1357–1362
Glover V (1996) Function of endogenous monoamine oxidase inhibitors. J Neural Transm (this volume)
Glover V, Reveley MA, Sandler M (1980) A monoamine oxidase inhibitor in human urine. Biochem Pharmacol 29: 467–470
Miller SB, Ditto B (1989) Individual differences in heart rate and peripheral vascular responses to an extended stress task. Psychophysiology 26: 506–513
Sandler M (1982) The emergence of tribulin. Trends Pharmacol Sci 3: 471–472
Turner JR, Carroll D (1985) Heart rate and oxygen consumption during mental arithmetic, a video game and graded excerise: further evidence of metabolically-exaggerated cardiac adjustments? Psychophysiology 22: 261–267
Willemsen GHM, de Geus EJC, Klaver CHAM, van Doornen LJP, Carroll D (1996) Ambulatory monitoring of the impedance cardiogram. Psychophysiology 33:184–193
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© 1998 Springer-Verlag Wien
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Clow, A. et al. (1998). Endogenous monoamine oxidase A inhibitory activity (tribulin), measured in saliva, is related to cardiovascular reactivity in normal individuals. In: Finberg, J.P.M., Youdim, M.B.H., Riederer, P., Tipton, K.F. (eds) MAO — The Mother of all Amine Oxidases. Journal of Neural Transmission. Supplement, vol 52. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6499-0_8
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DOI: https://doi.org/10.1007/978-3-7091-6499-0_8
Publisher Name: Springer, Vienna
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