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Hemodynamics in Physio- and Pathological Vessels

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Vascular Engineering

Abstract

Hemodynamics can be defined as the part of cardiovascular physiology dealing with the forces that drive the blood circulation in mammalian cardiovascular systems. A cardiovascular system is a series of blood vessels connected to the heart. Pressure generated in the heart propels blood through the system continuously. In this chapter, basic hemodynamics essential to interpretation of arterial disease in the aspect of bio-fluid mechanics are introduced. Hemodynamics in bio-fluid mechanics plays an important role in better understanding of clinical and pathological observations and in developing new methods for diagnosis in connection with mathematical models. In particular, hemodynamic factors, such as Wall Shear Stress and Oscillatory Shear Index, correlate substantially with the generation and progression of arterial disease including intimal thickening and atherosclerosis. In the larger vessels, such as the carotid artery, interaction between the vessel wall and the blood flow affects the distribution of hemodynamic factors.

The main scope of this chapter is to introduce hemodynamic applications of mathematical modeling of fluid mechanics. Mathematical models of fluid mechanics are used to quantify the hemodynamic factors and their relationship to vascular disease. The majority of all cardiovascular diseases and disorders are related to systemic hemodynamic dysfunction. Recent studies of cardiovascular diseases in relation to hemodynamic dysfunction are also briefly reviewed.

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Authors and Affiliations

  1. Department of Applied Physics, National Defense Academy, Yokosuka, Kanagawa, Japan

    Shigeru Tada

  2. Department of Biomedical Engineering, The City College of New York/CUNY, New York, NY, USA

    John M. Tarbell

Authors
  1. Shigeru Tada
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  2. John M. Tarbell
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Correspondence to Shigeru Tada .

Editor information

Editors and Affiliations

  1. Waseda University, Tokyo, Tokyo, Japan

    Kazuo Tanishita

  2. The University of Tokyo, Tokyo, Tokyo, Japan

    Kimiko Yamamoto

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Tada, S., Tarbell, J.M. (2016). Hemodynamics in Physio- and Pathological Vessels. In: Tanishita, K., Yamamoto, K. (eds) Vascular Engineering. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54801-0_4

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  • DOI: https://doi.org/10.1007/978-4-431-54801-0_4

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  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-54800-3

  • Online ISBN: 978-4-431-54801-0

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