Summary
The main method for brain hypothermia today is surface cooling using cooling blankets. However, surface cooling has posed a problem that requires a complicated technique and manpower for controlling the core temperature of hypothermia. We have devised a blood circuit for continuous hemodiafiltration and produced and used clinically two new blood cooling systems (MONAN and KANEM methods). Compared with surface cooling, these blood cooling systems have made it easy to control the core temperature during the periods of induction, cooling, and rewarming without being influenced by the patient’s body form. Moreover, postural drainage for preventing pulmonary infections, which were severe complications of hypothermia, is possible without use of a particular kinetic bed. Furthermore, it is possible improve the abnormal electrolytes seen with hypothermia, particularly hyperkalemia, at rewarming, by removing the humoral mediator that increases and courses the systemic inflammatory response syndrome. Based on our results, it is suggested that a blood cooling system using the MONAN and KANEM method is a useful technique for instituting brain hypothermia.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bigelow WG, Lindsay WK, Harrisson RC, Gordon RA, Greenwood WF (1950) Oxygen transport and utilization in dogs at low body temperatures. Am J Physiol 160:125
Boerema I, Wildschut A, Schmidt WJH, Broekhuysen L (1951) Experimental researches into hypothermia as an aid in the surgery of the heart. Arch Chir Neerl 3:25
Clifton GL, Allen S, Barrodale P, Plenger P, Berry J, Koch S, Fletcher J, Hayes RL, Choi SC (1993) A phase II study of moderate hypothermia in severe brain injury. J Neurotrauma 10:263–271
Fay T (1943) Observations on generalized refrigeration in caces of cerebral trauma. Assoc Res Nerv Ment Dis Proc 24:611–619
Forni LG, Hilton PJ (1997) Continuous hemofiltration in the treatment of acute renal failure. N Engl J Med 336:1303–1308
Hamilton DI, Shackleton J, Rees GJ, Abbott T (1973) Experience with deep hypothermia in infancy using core cooling. In: Barratt-Boyes BG, Neutze JM, Harris EA (eds) Heart disease in infancy. Baltimore, Williams8c Wilkins, p 52
Hirasawa H, Matuda K, Sugai T, Oda N (1998) Can continuous hemodiafiltration remove cytokines? Possibility of non-renal indication of continuous hemodiafiltration. Jpn Soc Intensive Care Med 5:345–355
Marion DW, Obrist WD, Carlier PM, Penrod LE, Darby JM (1993) The use of moderate therapeutic hypothermia for patients with severe head injuries, a preliminary report. J Neurosurg 79:354–362
Shiozaki T, Sugimoto H, Taneda M, Yoshida H, Iwai A, Yoshioka T, Sugimoto T (1993) Effect of mild hypothermia on uncontrollable intracranial hypertension after severe head injury. J Neurosurg 79:363–368
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2000 Springer-Verlag Tokyo
About this paper
Cite this paper
Okamoto, K., Nagao, K., Miki, T., Nitobe, E., Arima, K., Hayashi, N. (2000). New Hypothermia Method Using Blood Cooling System: MONAN and KANEM Method. In: Hayashi, N. (eds) Brain Hypothermia. Springer, Tokyo. https://doi.org/10.1007/978-4-431-66882-4_20
Download citation
DOI: https://doi.org/10.1007/978-4-431-66882-4_20
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-70277-1
Online ISBN: 978-4-431-66882-4
eBook Packages: Springer Book Archive