Abstract
During the past decade, 5 subjects with inflammatory bowel disease (1BD) and 3 with recurrent gastrointestinal cancer (RGC) developed symptomatic zinc deficiency during long term total parenteral nutrition (TPN). Characteristic skin lesions appeared earlier in IBD than in RGC (27.3 ± 13.6 vs 57.3 ± 4.9 days; p < 0.05). The plasma zinc levels at the onset were lower in RGC cases than those with IBD (12.0± 4.2 vs 23.8± 6.8µ g/dl). Doses Above 40 µ mol/day of parenteral zinc were necessary to improve plasma zinc levels.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Hankins DA, Riella MC, Scribner BH, Babb AL (1976) Whole blood trace element concentrations during total parenteral nutrition. Surgery 79: 674–677
Hendricks KM, Walker WA (1988) Zinc deficiency in inflammatory disease. Nutr Rev 46: 401–408
Hull RL (1974) Use of trace elements in intravenous hyperalimentation solutions. Am J Hosp Pharm 31: 759–761
James BE, MacMahon RA (1970) Trace elements in intravenous fluids. Med J Aust 19: 1161–1163
Jeejeeboy KN (1984) Micronutrients - state of the art. In: Ogoshi S,0kada A (ed) Parenteral and enteral hyperalimentation. Exerpta Medica, Asterdam New york Oxford, p 93
Kay RG, Tasman-Jones C(1975) Acute zinc deficiency in man during intravenous alimentation. Aus NZ J Surg 45: 325–330
Nishi M, Hiramatsu Y, Hatano T, Hioki K, Yamamoto M (1988) Effect of nutritional support as an adjunct to the treatment of esophageal cancer.In: Siewert JR, Holscher AH (ed) Disease of the esophagus. Springer, Berlin Heidelberg New york, p 2877
Okada A, Takagi Y, Itakura T, Satani M, Manabe H, Iida Y, Tanigaki T,Iwasaki M, Kasahara N (1976) Skin lesions during intravenous hyperalimentation: zinc deficiency. Surgery 80: 629–653
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Springer-Verlag Tokyo
About this paper
Cite this paper
Nishi, M., Takehara, H., Kita, Y., Komi, N. (1990). Clinical Study on Zinc Deficiency Receiving Total Parenteral Nutrition. In: Tomita, H. (eds) Trace Elements in Clinical Medicine. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68120-5_29
Download citation
DOI: https://doi.org/10.1007/978-4-431-68120-5_29
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68122-9
Online ISBN: 978-4-431-68120-5
eBook Packages: Springer Book Archive