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Adverse Effects of Regurgitant Duodenal Content on the Mucosa of the Residual Stomach After Partial Gastrectomy

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Recent Advances in Management of Digestive Cancers

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Abstract

Three groups of patients partially gastrectomized by Billroth II, Billroth I or pylorus-preserving procedure were evaluated for amount of bile acids in the gastric aspirate and histologic changes in the remnant gastric mucosa. The amount of bile acids was the highest and glandular dysplasia of the mucosa most predominant in the B-II group. Rats with either gastrojejunostomy or simple gastrotomy were maintained with an usual laboratory diet. Intestinal type adenoma and carcinoma developed exclusively in the gastrojejunostomized rats. Prolonged exposure of the gastric mucosa to bilious content may result in its histological changes that possibly lead to development of carcinoma.

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References

  1. Domellof L, Eriksson S, Jaunger KG (1975) Late occurrence of precancerous changes and carcinoma of the gastric stump after Billroth II resection. Acta Chir Scand 141:292–297.

    PubMed  CAS  Google Scholar 

  2. Morgernstern L, Yamakawa T, Seltzer D (1973) Carcinoma of the gastric stump. Am J Surg 125:29–38.

    Article  Google Scholar 

  3. Meister H, Schlag P, Weber E, Bockler R, Merkle P (1981) Frequency of cancerous and precancerous epithelial lesions in the stomach in different models for enterogastric reflux. Scand J Gastroenterol 16 (Suppl 67):165–168.

    Google Scholar 

  4. Morson BC, Sobin LH, Grundmann E, Johansen A, Nagayo T, Serck-Hanssen A (1980) Precancerous conditions and epithelial dysplasia in the stomach. J Clin Pathol 33:711–721.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Surgery, Hirosaki University School of Medicine, Hirosaki 036, Japan

    Ryukichi Hada, Yasunori Mikami, Dai Seito, Yuzuru Sugiyama, Hidetoshi Suzuki & Mitsuru Konn

  2. Department of Surgery, Hakodate Municipal Hospital, Hakodate, Hokkaido 040, Japan

    Masanori Ozawa

Authors
  1. Ryukichi Hada
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  2. Yasunori Mikami
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  3. Dai Seito
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  4. Yuzuru Sugiyama
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  5. Hidetoshi Suzuki
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  6. Mitsuru Konn
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  7. Masanori Ozawa
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Editor information

Editors and Affiliations

  1. The First Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, 602, Japan

    Toshio Takahashi M.D. (Professor and Chairman) (Professor and Chairman)

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© 1993 Springer-Verlag Tokyo

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Hada, R. et al. (1993). Adverse Effects of Regurgitant Duodenal Content on the Mucosa of the Residual Stomach After Partial Gastrectomy. In: Takahashi, T. (eds) Recent Advances in Management of Digestive Cancers. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68252-3_87

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  • DOI: https://doi.org/10.1007/978-4-431-68252-3_87

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68254-7

  • Online ISBN: 978-4-431-68252-3

  • eBook Packages: Springer Book Archive

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