Abstract
All the anti-inflammatory sources or drugs achieve their effects by blocking the increase in prostaglandin (PG) synthesis. PG synthesis is blocked by blocking the enzyme cyclooxygenase – an enzyme in arachidonic acid cascade for the synthesis of prostanoids. Mother Nature created these natural supplements eons ago, and it has been present in ecosystems for over a billion years. Hundreds of plant metabolites are reported to have many pharmacological activities although most of these reports are of academic interest and very few find entry at clinical trials. Compilation of the information would help promote wider acceptance and use of these nature-based drugs in mainstream of medicine. The present chapter is directed towards compilation of the pharmacological attributes of natural sources in the drug discovery and development process as it could be a driving force to identify lead molecules providing an attractive strategy for novel and improved therapeutics. In this chapter, we are going to reveal the name of these natural medicines and different sources available to us and what health benefits it provides to us to fight against inflammation.
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Jain, P., Pandey, R., Shukla, S.S. (2015). Natural Sources of Anti-inflammation. In: Inflammation: Natural Resources and Its Applications. SpringerBriefs in Immunology. Springer, New Delhi. https://doi.org/10.1007/978-81-322-2163-0_4
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