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Managing Perineural and Skull Base Involvement

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Non-melanoma Skin Cancer of the Head and Neck

Part of the book series: Head and Neck Cancer Clinics ((HNCC))

Abstract

Australia is recognized as the non-melanoma skin cancer (NMSC) capital of the world with approximately 300,000 cases diagnosed annually [1]. NMSC with perineural invasion (PNI) is an aggressive feature, which carries a worse prognosis through higher rates of locoregional recurrence and reduced survival [2–5]. NMSC with PNI has been shown to be associated with a disease-specific survival at 3 years of 64 %, compared to NMSC without PNI of 91 % [6].

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Acknowledgement

The authors wish to thank Dr Mitesh Gandhi for his input regarding radiological assessment and diagnosis.

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Authors and Affiliations

  1. Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Queensland, Princess Alexandra Hospital, QIMR Berghofer Institute of Medical Research, Brisbane, QLD, Australia

    Timothy A. Warren BSc (Hons), MBBS

  2. Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Queensland, Queensland Head and Neck Cancer Centre, Queensland Skull Base Unit, Princess Alexandra Hospital, Brisbane, QLD, Australia

    Benedict Panizza MBBS, MBA, FRACS

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  1. Timothy A. Warren BSc (Hons), MBBS
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  2. Benedict Panizza MBBS, MBA, FRACS
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Correspondence to Timothy A. Warren BSc (Hons), MBBS .

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Editors and Affiliations

  1. University of Sydney, Westmead Hospital, Sydney, Australia

    Faruque Riffat

  2. Westmead Hospital, University of Sydney, Sydney, Australia

    Carsten E. Palme

  3. Westmead Hospital, University of Sydney, Sydney, Australia

    Michael Veness

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© 2015 Faruque Riffat, Carsten E. Palme, Michael Veness, Rehan Kazi, Raghav C. Dwivedi

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Warren, T.A., Panizza, B. (2015). Managing Perineural and Skull Base Involvement. In: Riffat, F., Palme, C., Veness, M. (eds) Non-melanoma Skin Cancer of the Head and Neck. Head and Neck Cancer Clinics. Springer, New Delhi. https://doi.org/10.1007/978-81-322-2497-6_9

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  • DOI: https://doi.org/10.1007/978-81-322-2497-6_9

  • Publisher Name: Springer, New Delhi

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  • Online ISBN: 978-81-322-2497-6

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