Abstract
Pre-Descemet’s endothelial keratoplasty (PDEK) is a technique of endothelial keratoplasty (EK) that was described by one of the authors (Prof. Amar Agarwal) and Prof. Harminder Dua where the Pre-Descemet’s layer (PDL) is also transplanted along with the Descemet’s membrane (DM) and endothelium [1]. It thus differs from Descemet’s membrane endothelial keratoplasty (DMEK) [2, 3] in which only the Descemet’s membrane and endothelium are transferred. It also differs from Descemet’s stripping automated endothelial keratoplasty (DSAEK) [4] and ultra-thin DSAEK (UT-DSAEK) [5, 6] in not transferring stroma. The PDL has been described as a cellular, measuring about 10–15 μm, and composed of 10–15 lamellae made of type I collagen bundles arranged in transverse, longitudinal and oblique directions (Fig. 12.1) [7].
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References
Agarwal A, Dua HS, Narang P, Kumar DA, Agarwal A, Jacob S, Agarwal A, Gupta A. Pre-Descemet’s endothelial keratoplasty (PDEK). Br J Ophthalmol. 2014;98(9):1181–5.
Dapena I, Ham L, Melles GRJ. Endothelial keratoplasty: DSEK/DSAEK or DMEK – the thinner the better? Curr Opin Ophthalmol. 2009;20:299–307.
Dapena I, Moutsouris K, Droutsas K, et al. Standardized “no-touch” technique for Descemet membrane endothelial keratoplasty. Arch Ophthalmol. 2011;129:88–94.
Gorovoy MS. Descemet-stripping automated endothelial keratoplasty. Cornea. 2006;25:886–9.
Busin M, Madi S, Santorum P, Scorcia V, Beltz J. Ultrathin descemet’s stripping automated endothelial keratoplasty with the microkeratome double-pass technique: two-year outcomes. Ophthalmology. 2013;120(6):1186–94.
Busin M, Albé E. Does thickness matter: ultrathin Descemet stripping automated endothelial keratoplasty. Curr Opin Ophthalmol. 2014;25(4):312–8.
Dua HS, Faraj LA, Said DG, Gray T, Lowe J. Human corneal anatomy redefined: a novel pre-Descemet’s layer (Dua’s layer). Ophthalmology. 2013;120(9):1778–85.
Ashton Acton. Epithelial cells—Advances in research and application: 2013 edition. Scholarly Editions. Chapter 4: Endothelial cells, Pg 368
Bennett A, Mahmoud S, Drury D, Dwight CH, McCulley J, Matthew PW, Vinod MV. Impact of donor age on corneal endothelium-descemet membrane layer scroll formation. Eye Contact Lens: Sci Clin Pract. 2015;41(Issue 4):236–9.
Kobayashi A, Yokogawa H, Yamazaki N, Masaki T, Sugiyama K. Endothelial keratoplasty with infant donor tissue. Clin Ophthalmol. 2014;8:1827–30.
Agarwal A, Agarwal A, Narang P, Kumar DA, Jacob S. Pre-descemet endothelial keratoplasty with infant donor corneas: a prospective analysis. Cornea. 2015;34(8):859–65.
Agarwal A. Trocar anterior chamber maintainer facilitates ocular surgeries. Ocular Surgery News U.S. Edition, July 10, 2015
Jacob S, Agarwal A, Agarwal A, Narasimhan S, Kumar DA, Sivagnanam S. Endoilluminator-assisted transcorneal illumination for Descemet membrane endothelial keratoplasty: enhanced intraoperative visualization of the graft in corneal decompensation secondary to pseudophakic bullous keratopathy. J Cataract Refract Surg. 2014;40(8):1332–6.
Burkhart ZN, Feng MT, Price MO, Price FW. Handheld slit beam techniques to facilitate DMEK and DALK. Cornea. 2013;32(5):722–4.
Veldman PB, Dye PK, Holiman JD, Mayko ZM, Sáles CS, Straiko MD, Stoeger CG, Terry MA. Stamping an S on DMEK Donor tissue to prevent upside-down grafts: laboratory validation and detailed preparation technique description. Cornea. 2015 Sep;34(9):1175-8.
Cost B, Goshe JM, Srivastava S, Ehlers JP.Intraoperative Optical Coherence Tomography-Assisted Descemet Membrane Endothelial Keratoplasty in the DISCOVER Study. Am J Ophthalmol. 2015 Sep;160(3):430-7.
Saad A, Guilbert E, Grise-Dulac A, Sabatier P, Intraoperative GD. Intraoperative OCT-assisted DMEK: 14 consecutive cases. Cornea. 2015;34(7):802–7.
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Jacob, S., Agarwal, A. (2016). Pre-Descemet’s Endothelial Keratoplasty. In: Jacob, S. (eds) Mastering Endothelial Keratoplasty. Springer, New Delhi. https://doi.org/10.1007/978-81-322-2818-9_12
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DOI: https://doi.org/10.1007/978-81-322-2818-9_12
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