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Pancreatic Cancer: Pathological Factors and TNM Staging

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Surgical Treatment of Pancreatic Diseases

Part of the book series: Updates in Surgery ((UPDATESSURG))

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Abstract

Ductal adenocarcinoma, a solid, exocrine epithelial neoplasm, represents with its variations the large majority of primitive malignant tumors of the pancreas (about 90% of cases) [1]. It is typically characterized by insidious growth with a generally unfavorable prognosis. At the time of diagnosis in most cases there are already peripancreatic lymph node metastases, and at post mortem, liver (80%), peritoneal (60%), pulmonary (50–70%), and suprarenal metastases (25%) are also frequently found [2]. Despite the recent knowledge acquired in the biomolecular genetics of this neoplasm and the progress made in instrumental diagnostic technology, the prognosis of this tumor is still poor, with an average survival of 19% at 1 year after diagnosis and 2–4% after 5 years: pancreatic cancer still has the worst prognosis of the solid neoplasms [3].

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  1. Division of Minimally Invasive Surgery, Ospedali Riuniti University Hospital, Polytechnic University of Marche, Ancona, Italy

    Angelo de Sanctis, Massimiliano Rimini & Mario Guerrieri

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  1. Angelo de Sanctis
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  2. Massimiliano Rimini
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de Sanctis, A., Rimini, M., Guerrieri, M. (2009). Pancreatic Cancer: Pathological Factors and TNM Staging. In: Surgical Treatment of Pancreatic Diseases. Updates in Surgery. Springer, Milano. https://doi.org/10.1007/978-88-470-0856-4_15

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  • DOI: https://doi.org/10.1007/978-88-470-0856-4_15

  • Publisher Name: Springer, Milano

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