Abstract
The primary objective of intensive care is to prevent and treat secondary brain injury (SBI) caused by hypotension, hypoxia, or hyperthermia. We will focus this chapter on traumatic brain injury (TBI) and our objective will be the treatment and prevention of SBI using a neuroprotective strategy to maintain cerebral perfusion in order to meet the brain’s oxygen and metabolic demands. Elevated intracranial pressure (ICP) is an important cause of SBI and associated with very poor outcome after TBI. Elevated ICP can be related to brain edema, vascular engorgement, cerebral contusion, or intracranial mass lesions. The prevention and control of raised ICP and the maintenance of cerebral perfusion pressure (CPP) are essential therapeutic goals after TBI. ICP monitoring has developed an essential role in the treatment of TBI, despite the incredible absence of class-1 studies and its use is only recommended by international consensus guidance [1].
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Maciel, F.M.B. (2009). Central Nervous System Monitoring. In: Gullo, A., Lumb, P.D., Besso, J., Williams, G.F. (eds) Intensive and Critical Care Medicine. Springer, Milano. https://doi.org/10.1007/978-88-470-1436-7_12
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DOI: https://doi.org/10.1007/978-88-470-1436-7_12
Publisher Name: Springer, Milano
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