Abstract
The correlation between inflammatory bowel disease (IBD) and articular involvement has long been well known, but a nosographic classification was proposed only in the early 1970s, when two clinical forms of chronic intestinal inflammation were identified: Crohn’s disease (CD) and ulcerative colitis (UC). Both conditions were considered to be responsible for the peculiar forms of arthritis seen in a subset of patients with seronegative spondyloarthritides (SnSp) (Fig. 18.1) [1]. Numerous clinical and experimental findings subsequently drew strong attention to the enormous relevance of the relationship between IBD and either axial or peripheral articular inflammations [2,3].
Linical conditions belonging to the group of seronegative spondyloarthritides (SnSp). IBD. inflammatory bowel disease: SAPHO, synovitis, acne, pustulosis, hyperostosis, osteitis
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References
Wright V, Moll JMH (eds) (1976) Seronegative polyarthritis. Holland Publishing Company, Amsterdam
Dekker-Sayes BJ, Meuwissen SG, Van Den Berg-Loonen EM et al (1978) Ankylosing spondylitis and inflammatory bowel disease. II. Prevalence of peripheral arthritis, sacroiliitis, and ankylosing spondylitis in patients suffering from inflammatory bowel disease. Ann Rheum Dis 37:33–35
Rynes RI, Volastro PS, Bartholomew LE (1984) Exacerbation of B27 positive spondyloarthropathy by enteric infections. J Rheumatol 11:96–97
Ebringer A, Ghuloom M (1986) Ankylosing spondylitis, HLA-B27, and Klebsiella: cross reactivity and antibody studies. Ann Rheum Dis 45:703–704
Mielants H, Veys EM, Cuvelier C et al (1987) Significance of gut inflammation in the seronegative spondyloarthropathies. Clin Exp Rheum 5 Suppl 1:S81–S87
Das KM (1999) Relationship of extraintestinal involvement in inflammatory bowel disease. Dig Dis Sci 44:1–13
Orchard TR, Wordsworth BP, Jewell DP (1998) Peripheral arthropaties in inflammatory bowel disease: their articular distribution and natural history. Gut 42:387–391
Repiso A, Alcántara M, Muñoz-Rosas C et al (2006) Extraintestinal manifestations of Crohn’s disease: prevalence and related factors. Rev Esp Enferm Dig 98:510–517
Ardizzone S, Sarzi Puttini P, Cassinotti A, Bianchi Porro G (2008) Extraintestinal manifestations of inflammatory bowel disease. Dig Liver Dis 40 Suppl 2:S253–S259
Mader R, Segol O, Adawi M et al (2005) Arthritis or vasculitis as presenting symptoms of Crohn’s disease. Rheumatol Int 25:401–405
Fornaciari G, Salvarani C, Beltrami M et al (2001) Musculoskeletal manifestations in inflammatory bowel disease. Can J Gastroenterol 15:339–403
Steer S, Jones H, Hibbert J et al (2003) Low back pain, sacroiliitis, and the relationship with HLA-B27 in Crohn-s disease. J Rheumatol 30:518–522
Farmer RG, Michener WM (1979) Prognosis of Crohn’s disease with onset in childhood or adolescence. Dig Dis Sci 24:752–757
Hamilton JR, Bruce GA, Abdurrahman M, Gall DG (1979) Inflammatory bowel disease in children and adolescent. Adv Pediatr 26:311–41
Holden W, Orchard T, Wordsworth P (2003) Enteropathic arthritis. Rheum Dis Clin N Am 29:513–530
Sand born WJ, Stemson WF, Brinson J et al (2006) Safety of celecoxib in patients with ulcerative colitis in remission: a randomized, placebo-controlled, pilot study. Clin Gastroenterol Hepatol 4:203–211
Van den Bosch F, Kruithof E, De Vos M et al (2000) Crohn’s disease associated with spondyloarthropathy: effect of TNF-a blockade with infliximab on the articular symptoms. Lancet 356:1821–1822
De Keyser F, Baeten D, Van den Bosch F et al (2003) Infliximab in patients who have spondyloarthropathy: clinical efficacy, safety, and biological immunomodulation. Rheum Dis Clin North Am 29:463–479
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Minisola, G., Famularo, G. (2010). Rheumatological Manifestations of Crohn’s Disease. In: Tersigni, R., Prantera, C. (eds) Crohn’s Disease. Updates in Surgery. Springer, Milano. https://doi.org/10.1007/978-88-470-1472-5_18
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DOI: https://doi.org/10.1007/978-88-470-1472-5_18
Publisher Name: Springer, Milano
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