Abstract
Several studies and increasing clinical experience suggest that interventricular resychronization can play an important role in the therapy of congestive heart failure (CHF) that is refractory to standard drug treatment. A remarkable percentage of CHF patients present with a delay in interventricular conduction and often with an ECG pattern of left bundle branch block (LBBB). The delayed left ventricular activation has detrimental effects on diastolic ventricular filling, with E wave and A wave overlapping, and can result in functional mitral regurgitation [1,2]. In addition, desynchronization of myocardial contraction in the right and left ventricles (RV, LV) impairs the pump function, reducing the stroke volume (SV), and increasing the physical stress to the heart [3,4].
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Schnittger I, Appleton CP, Hatle LK et al (1988) Diastolic mitral and tricuspid regurgitation by Doppler echocardiography in patients with atrioventricular block: new insight into the mechanism of atrioventricular valve closure. J Am Coll Cardiol 11:83–88
Auricchio A, Stellbrink C, Block M et al (1999) The effect of pacing chamber and atrio-ventricular delay on acute systolic function of paced patients with congestive heart failure. Circulation 99:2993–3001
Grines CL, Bashore TM, Boudoulas H et al (1989) Functional abnormalities in isolated left bundle branch block. The effect of interventricular asynchrony. Circulation 79:845–853
Xiao HB, Brecker SJD, Gibson DG (1992) Effects of abnormal activation on the time course of the left ventricular pressure pulse in dilated cardiomyopathy. Br Heart J 68:403–407
Curnis A, Mascioli G, Bontempi L et al (2002) Biventricular pacing: criteria for easier implantation procedure. In: Adornato E (ed) Progress on diagnosis and treatment of cardiac arrhythmias. Edizioni Luigi Pozza, Rome, pp 181–186
Pappone C, Rosanio S, Gulletta S et al (2000) Technological lead innovations and best sites for left ventricular pacing in patients with heart failure. In: Adornato E (ed) Cardiac arrhythmias: how to improve the reality in the third millennium? Edizioni Luigi Pozza, Rome, pp 369–375
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2003 Springer-Verlag Italia
About this paper
Cite this paper
Dorticós, F., Mazzone, P., Zayas, R., Quiñones, M.A., Castro, J., Di Gregorio, F. (2003). New Advances in Biventricular Pacing: Improving Ventricular Sensing Function. In: Gulizia, M. (eds) New Advances in Heart Failure and Atrial Fibrillation. Springer, Milano. https://doi.org/10.1007/978-88-470-2087-0_65
Download citation
DOI: https://doi.org/10.1007/978-88-470-2087-0_65
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-2169-3
Online ISBN: 978-88-470-2087-0
eBook Packages: Springer Book Archive