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Pathophysiology of Liver Dysfunction in Sepsis

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Sepsis and Organ Dysfunction
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Abstract

Liver dysfunction is commonly associated with critical illness. Up to 54% of patients admitted to intensive care units present abnormal liver function tests. Severe liver dysfunction is reported to occur in 12–95% of adult respiratory distress syndrome patients and liver blood tests on the first day of diagnosis are predictive of survival [1]. Liver failure is a critical determinant of mortality in trauma [2], in intra-abdominal sepsis [2], and after cardiopulmonary bypass surgery [3].

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© 2000 Springer-Verlag Italia

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Brienza, N. (2000). Pathophysiology of Liver Dysfunction in Sepsis. In: Baue, A.E., Berlot, G., Gullo, A., Vincent, JL. (eds) Sepsis and Organ Dysfunction. Springer, Milano. https://doi.org/10.1007/978-88-470-2284-3_11

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  • DOI: https://doi.org/10.1007/978-88-470-2284-3_11

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0096-4

  • Online ISBN: 978-88-470-2284-3

  • eBook Packages: Springer Book Archive

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