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Nanoinformatics: Developing Advanced Informatics Applications for Nanomedicine

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Intracellular Delivery

Part of the book series: Fundamental Biomedical Technologies ((FBMT,volume 5))

Abstract

In this chapter we introduce a new informatics field called “Nanoinformatics” based on our own research and on consensus work carried out under the auspices of the US National Cancer Institute (NCI) and the European Commission (EC). Nanoinformatics can be defined as the “use of informatics techniques for analyzing and processing information about the structure and physicochemical characteristics of nanoparticles, their environments, and applications”. Its goal is to use information to accelerate research in nanomedicine. We summarize various areas of research and applications, such as ontologies and semantic search, text mining, imaging, standards, together with an example of the research our group has performed in this field on text mining for extracting information about nanotoxicity from the literature.

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Abbreviations

BI:

Bioinformatics

BMI:

Biomedical Informatics

EC:

European Commission

HIS:

Hospital Information Systems

IMIA:

International Medical Informatics Association

MI:

Medical Informatics

NCI:

National Cancer Institute

NIH:

National Institutes of Health

NIOSH:

National Institute for Occupational Safety and Health

NPO:

NanoParticle Ontology

NSF:

National Science Foundation

NT:

Nanomedicine Taxonomy

ONAMI:

Oregon Nanoscience and Microtechnologies Institute

PMID:

PubMed Identifier

QM/MM:

Quantum Mechanics and Molecular Mechanics

TM:

Text Mining

UMLS:

Unified Medical Language System

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Acknowledgments

The present work has been funded, in part, by the ACTION-Grid support action (FP7-ICT-2007-2-224176), the Spanish Ministry of Science and Innovation (FIS/AES PS09/00069 and COMBIOMED-RETICS), the Ibero-NBIC network (CYTED 209RT0366), the European Commission through the ACGT integrated project (FP6-2005-IST-026996), and the Comunidad de Madrid, Spain.

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Authors and Affiliations

  1. Departamento Inteligencia Artificial, Facultad de Informatica, Biomedical Informatics Group, Universidad Politécnica de Madrid, Campus de Montegancedo, Madrid, Spain

    Victor Maojo, Miguel García-Remesal, Diana de la Iglesia, José Crespo, David Pérez-Rey & Stefano Chiesa

  2. Nanotechnology Characterization Laboratory and SAIC-Frederick of Computer Science, National Cancer Institute, US National Institutes of Health, Baltimore, MD, USA

    Martin Fritts

  3. Department of Computer Science, Rutgers, The State University of New Jersey, Newark, NJ, USA

    Casimir A. Kulikowski

Authors
  1. Victor Maojo
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  2. Miguel García-Remesal
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  3. Diana de la Iglesia
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  4. José Crespo
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  5. David Pérez-Rey
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  6. Stefano Chiesa
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  7. Martin Fritts
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  8. Casimir A. Kulikowski
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Corresponding author

Correspondence to Victor Maojo .

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Editors and Affiliations

  1. , Chemical and Biological Engineering, Vanderbilt University, VU Station B 351604, Nashville, 37235, Tennessee, USA

    Aleš Prokop

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Maojo, V. et al. (2011). Nanoinformatics: Developing Advanced Informatics Applications for Nanomedicine. In: Prokop, A. (eds) Intracellular Delivery. Fundamental Biomedical Technologies, vol 5. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1248-5_26

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