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Biomedical Applications of Induced Pluripotent Stem Cells

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Stem Cells and Cancer Stem Cells,Volume 3

Part of the book series: Stem Cells and Cancer Stem Cells ((STEM,volume 3))

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Abstract

The generation of induced pluripotent stem (iPS) cells from differentiated somatic cells offers innovative biomedical applications that are significantly advancing human medicine. Patient-specific iPS cells can self-renew indefinitely and serve as a limitless source of autologous cells to treat a number of human degenerative diseases without the risk of immune rejection. In the near-term, iPS cells from patients with inheritable disorders will offer novel platforms for dissecting disease mechanisms, identifying new molecular therapeutic targets and pharmacological/toxicological testing for drug discovery. But several challenges in validating safety of iPS cells exist before its potential in clinical therapeutics can be realized.

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Authors and Affiliations

  1. Department of Animal Science, Cornell University, Ithaca, NY, 14853, USA

    Vimal Selvaraj

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  1. Vimal Selvaraj
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Correspondence to Vimal Selvaraj .

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  1. , Kean University, Room 213, Library building, Morris Avenue 1000, Union, 07083, New Jersey, USA

    M.A. Hayat

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Selvaraj, V. (2012). Biomedical Applications of Induced Pluripotent Stem Cells. In: Hayat, M. (eds) Stem Cells and Cancer Stem Cells,Volume 3. Stem Cells and Cancer Stem Cells, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-2415-0_27

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