Skip to main content

Application of Ion Exchange Resins in Kidney Dialysis

  • Chapter
  • First Online:
Ion Exchange Technology II

Abstract

Besides the proved applications of ion exchange resins (IER) in various industries, biochemists have found their uses in medicines also. The development and use of synthetic ion exchange resins for kidney dialysis is a relatively recent achievement. The artificial kidney uses cellulose membranes in place of the phospholipid-bilayer membranes used by real kidneys to separate the components of blood. Polymeric ion exchange resins are insoluble, so when taken orally, pass through gastrointestinal tract (GIT) without being absorbed. In malfunctioned kidney, sodium and calcium polystyrene sulfonate resins are designed to exchange sodium for potassium in the colon, for use in the treatment of hyperkalemia. It is predicted that additional therapeutic applications may be found for ion exchange resins in the coming years.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. McPhie P (1971) Dialysis Method Enzymol 22:23–33

    Google Scholar 

  2. McCready RM, Hassid WZ (1943) J Am Chem Soc 65:1154

    Article  CAS  Google Scholar 

  3. Reid AF, Jones F (1949) Am J Clin Path 19:10

    CAS  Google Scholar 

  4. Richardson RW (1949) Nature (Lond) 164:916

    Article  CAS  Google Scholar 

  5. Slinin Y, Foley RN, Collins AJ (2005) Calcium, phosphorus, parathyroid hormone, and cardiovascular disease in hemodialysis patients: the USRDS waves 1, 3, and 4 study. J Am Soc Nephrol 16:1788–1793

    Article  CAS  Google Scholar 

  6. Block GA, Hulbert-Shearon TE, Levin NW, Port FK (1998) Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: a national study. Am J Kidney Dis 31:607–617

    Article  CAS  Google Scholar 

  7. Haagen K, Helfferich F (1961) Ion-exchange membrane. Germany Patent 971,729

    Google Scholar 

  8. Block GA, Spiegel DM, Ehrlich J et al (2005) Effects of sevelamer and calcium on coronary artery calcification in patient of hemodialysis. Kidney Int 68:1815–1824

    Article  CAS  Google Scholar 

  9. Markus K (2006) European Renal & Genito - Urinary Disease, pp 18–21

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Fazal-Ur-Rehman .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer Science+Business Media B.V.

About this chapter

Cite this chapter

Fazal-Ur-Rehman, Khan, S.N. (2012). Application of Ion Exchange Resins in Kidney Dialysis. In: Inamuddin, D., Luqman, M. (eds) Ion Exchange Technology II. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-4026-6_8

Download citation

Publish with us

Policies and ethics