Abstract
Functional neuroimaging techniques measure hemodynamic response as an indirect indicator of neuronal activity. These imaging techniques consider only forward pathway (neuron → astrocyte → vessel) and often the effect of metabolic feedback on neural activity is ignored. To understand brain’s computation, we propose a biophysical model of neuro-glial-vascular interaction forming a functional loop. This model describes key biochemical signaling pathways involved in astrocyte mediated neuro vascular coupling using a series of first order nonlinear differential equations.
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Chander, B.S., Chakravarthy, V.S. (2013). A Biophysical Model of Neuro-Glial-Vascular Interactions. In: Yamaguchi, Y. (eds) Advances in Cognitive Neurodynamics (III). Springer, Dordrecht. https://doi.org/10.1007/978-94-007-4792-0_10
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DOI: https://doi.org/10.1007/978-94-007-4792-0_10
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