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Amphiphilic Molecules in Drug Delivery Systems

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Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment

Part of the book series: Advances in Predictive, Preventive and Personalised Medicine ((APPPM,volume 4))

Abstract

Numerous drug delivery colloidal systems are formulated using polymers or surfactants or a mixture of both, typically due to their self-assembly properties. Molecular self-assembly creates the possibility to dissolve and protect drugs from adverse external environments. Therefore, it is important to understand the interactions behind the self-assembly phenomena of surfactant and polymer molecules, polymer-polymer and polymer-surfactant mixtures. A number of colloidal structures used in drug delivery formulations such as micelles, vesicles, liquid crystalline phases, microemulsions, polymer gels, aerosols, polymer-polymer and polymer-surfactant complexes will be illustrated in this chapter and their main physicochemical properties will be highlighted, keeping in mind their relevance to the drug delivery research field.

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Authors and Affiliations

  1. Department of Chemistry, University of Coimbra, Rua Larga, 3004-535, Coimbra, Portugal

    Salomé dos Santos & Filipe E. Antunes

  2. Institute for Biotechnology and Bioengineering, Centre of Genomics and Biotechnology (IBB/CGB), Faculty of Sciences and Technology, University of Algarve, Campus de Gambelas, Ed. 8, 8005-139, Faro, Portugal

    Bruno Medronho

  3. Centre for BioNano Interactions, School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland

    Tiago dos Santos

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  1. Salomé dos Santos
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  2. Bruno Medronho
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  3. Tiago dos Santos
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  4. Filipe E. Antunes
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Correspondence to Filipe E. Antunes .

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  1. , Chemical Engineering, University of Coimbra, Rua Silvio Lima, Coimbra, 3030 790, Portugal

    Jorge Coelho

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Santos, S.d., Medronho, B., Santos, T.d., Antunes, F.E. (2013). Amphiphilic Molecules in Drug Delivery Systems. In: Coelho, J. (eds) Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment. Advances in Predictive, Preventive and Personalised Medicine, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-6010-3_2

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