Abstract
Over 30 years ago the elegant radioisotopic experiments by Quayle and his colleagues have led to a discovery of the novel metabolic pathway, the ribulose monophosphate (RuMP) cycle. Further enzymic studies confirmed its operation in many obligately and facultatively methylotrophic bacteria of different taxonomic position. A detailed presentation of four possible variants of this cycle has been reviewed elsewhere (Quayle, 1980). This paper briefly describes a new variant of the RuMP cycle coupled with pyrophosphate-dependent 6-phosphofructokinase (PPi-PFK) and its operation in Type (obligate methanotrophs. Current state and future prospects for our studies on the metabolic role of inorganic pyrophosphate (PPi) in aerobic methylotrophs are also discussed.
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© 1996 Kluwer Academic Publishers
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Trotsenko, Y.A., Khmelenina, V.N., Beschastny, A.P. (1996). The Ribulose Monophosphate (Quayle) Cycle: News and Views. In: Lidstrom, M.E., Tabita, F.R. (eds) Microbial Growth on C1 Compounds. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0213-8_2
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DOI: https://doi.org/10.1007/978-94-009-0213-8_2
Publisher Name: Springer, Dordrecht
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