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Central 5-hydroxytryptamine (5-HT) and its effect on the cardiovascular system

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Cardiovascular Pharmacology of 5-Hydroxytryptamine

Abstract

The existence of discrete 5-HT-containing neurones in the brain stem with extensive ramifications to neuroanatomical regions involved in cardiovascular regulation has been known for more than two decades [1]. Our understanding, however, of the intricate interactions of the 5-HT networks and central autonomic pathways has been rather slow to evolve [2–4]. Thus, despite substantial evidence implicating an important role for central 5-HT neurotransmission in blood pressure regulation, the precise nature of this role remains unclear.

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Authors
  1. A. K. Mir
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  2. J. R. Fozard
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Editor information

Editors and Affiliations

  1. Department of Pharmacology, Erasmus University, Rotterdam, The Netherlands

    P. R. Saxena

  2. Department of Physiology, University of Wales, College of Cardiff, Cardiff, UK

    D. I. Wallis

  3. Department of Pharmacology, Duphar B.V, Weesp, The Netherlands

    W. Wouters  & P. Bevan  & 

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Mir, A.K., Fozard, J.R. (1990). Central 5-hydroxytryptamine (5-HT) and its effect on the cardiovascular system. In: Saxena, P.R., Wallis, D.I., Wouters, W., Bevan, P. (eds) Cardiovascular Pharmacology of 5-Hydroxytryptamine. Developments in CardioCardiovascular Pharmacology of 5-Hydroxytryptamine, vol 106. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0479-8_18

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  • DOI: https://doi.org/10.1007/978-94-009-0479-8_18

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6701-0

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