Abstract
Resistance or susceptibility to the development of tumors induced by Marek’s disease virus or Rous sarcoma virus in chickens is controlled by the major histocompatibility B complex. The recent cloning of chicken B complex B-L (class II), B-F (class I) and B-G (class IV) genes has provided new tools for molecular genotyping which should complement available serological and cellular assays and help identifying the B complex genes involved in disease control. The identification of 22 genes in the 320 kb of the B complex which have been cloned make it a prime target for a large scale collaborative sequencing project.
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References
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© 1989 ECSC,EAEC,Brussels and Luxembourg
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Auffray, C. (1989). Molecular Anatomy of the Chicken Major Histocompatibilty B Complex. In: Improving Genetic Disease Resistance in Farm Animals. Current Topics in Veterinary Medicine and Animal Science, vol 52. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1057-7_11
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DOI: https://doi.org/10.1007/978-94-009-1057-7_11
Publisher Name: Springer, Dordrecht
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