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Effusions

  • Chapter
Local Invasion and Spread of Cancer

Part of the book series: Cancer Growth and Progression ((CAGP,volume 7))

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Abstract

Effusions may develop in any of the serous membrane-lined body cavities. The peritoneal, pleural, and pericardial spaces are the principal mesothelial-lined body cavities that cause clinical diagnostic problems. All three major body cavities share the characteristic that they are normally more accurately described as potential spaces. When fluid of any type develops in this “potential space”, it separates the layers of the body cavity. Excessive accumulation of fluid may result in compromise of normal organ functions. In this respect, the heart is particularly subject to the effects of fluid accumulation in the pericardial sac. Compromise of ventricular filling in diastole may result in cardiac tamponade and rapid death. In the pleural cavities, fluid accumulation will lead to respiratory compromise by preventing normal lung expansion. Fluid accumulation is perhaps best tolerated in the peritoneal cavity, but eventually this also results in discomfort, respiratory compromise, and difficulty with mobility.

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Authors
  1. Rudolf C. Ulirsch
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  2. Dena M. Gomez
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  1. Department of Immunology and Infectious Diseases, Pfizer Central Research, Groton, Conn., USA

    Kenneth W. Brunson

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Ulirsch, R.C., Gomez, D.M. (1989). Effusions. In: Brunson, K.W. (eds) Local Invasion and Spread of Cancer. Cancer Growth and Progression, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1093-5_18

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  • DOI: https://doi.org/10.1007/978-94-009-1093-5_18

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