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Immunology of Gonorrhoea

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Immunology of Sexually Transmitted Diseases

Part of the book series: Immunology and Medicine ((IMME,volume 9))

Abstract

Neisseria gonorrhoeae colonizes and infects the mucosal surfaces of man and is particularly well adapted to survival in the genitourinary tract. The problem with gonorrhoea is that there is no apparent natural immunity and little evidence of acquired immunity. The host response to infection is often characterized by the appearance of polymorphonuclear neutrophils (PMN). Intracellular Gram-negative cocci, first described by Neisser, are still regarded as pathognomonic for gonococcal urethritis in males. However, it is not known whether PMNs play a major role in resolving the infection.

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Ison, C.A. (1988). Immunology of Gonorrhoea. In: Wright, D.J.M. (eds) Immunology of Sexually Transmitted Diseases. Immunology and Medicine, vol 9. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1255-7_5

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