Abstract
Some years ago a theory was developed (2) that still serves as the basis of present day hypotheses. It states that the cancerous information is contained in the DNA of all cells. This will be effective, however, only when those proteins are removed which block the transcription of this cancerous information. Once these nucleoproteins have been released, proteins are produced according to the code of the generally blocked gene in the DNA. The function of those proteins, which are present only in a low concentration in the normal cell, is of enzymatic nature. They will interfere with the metabolism of a cell, which may end up in such a strong disarray of its self-regulation that a cancerous state of the cell develops.
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References
Aaronson SA: Lecture at the International NFCR Symp., Washington, DC, 1984
Busch H: Antigens of neoplastic cells. In Biochemistry of the Cancer Cell, Academic Press, New York, pp. 292–312, 1962
Cheng EH, Furth ME, Scolnick EM, Lowy DR: Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus. Nature 297:479–483, 1982
Davydov AS: Solutions in molecular systems. Phys Scripta 20:387–394, 1979
Ladik J: Treatment of a periodicity and correlation in polymers. Int J Quant Chem 23:1073–1081, 1983
Ladik J: In Structure and Dynamics: Nucleic Acids and Proteins Clementi E, Sarma R (Eds.), New York: Academic Press, 1983
Ladik J: In Quantum Chemistry of Polymers; Solid State Aspects, Ladik J, Andre J-M, D. Reidel (Eds.), Publ. Co., Dordrecht, p. 337 +, 1984
Ladik J: Proceedings of “Structure and Dynamics of DNA, Proteins and Membranes”. Rome Clementi E, Sarma RS (eds), New York, Academic Press, 1983, p. 261
Ladik J, Cizek J, Int J Quant Chem 26:155, 1984
Ladik J, Seel M In Proc of Int Conf on Systems Research, Informatics and Cybernetics”, Baden-Baden (in press)
Ladik J, Seel M: Int J Quant Chem QBS 12:235–244, 1985
Ladik J, Suhai S, Seel M: Int J Quant Chem QBS 5:35–49,1978
Laki K, Ladik J: Int J Quant Chem QBS 35 1976
Otto P, Ladik J, Liu SC: Theochem 123:129 1985
Pincus MR, van Ransoude J, Harford JB, Chang EH, Carty RP, Klausner RD: Proc Natl Acad Sci USA 180:5253 1983
Rechavi E, Givol D, Canaani E: Nature 300:607 1982
Santos E, Tronick SR, Aaronson SA, Pulciani S, Barbacid M: Nature 298:343 1982:
Tabin CJ, Bradley SM, Bargemann CT, Weinberg RH, Papageorge AC, Scolnick EM, Dhar R, Lowy DR, Chang EH: Nature 300:143 1982
Weinstein B: Personal communication
Welch GR: Progr Biophys Molec Biol 32:103 1978
Yuasa Y, Scrivasta SK, Dunn CY, Rhim JS, Reddy P, Aaronson SA: Nature 303:775 1983
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© 1989 Kluwer Academic Publishers, Dordrecht
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Ladik, J., Otto, P. (1989). The Quantum Theory of Carcinogenesis — A Short Review. In: Weisburger, E.K. (eds) Mechanisms of Carcinogenesis. Cancer Growth and Progression, vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2526-7_9
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DOI: https://doi.org/10.1007/978-94-009-2526-7_9
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-7641-8
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