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Cardioplegia

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International Practice in Cardiothoracic Surgery

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Abstract

Cross-clamping the ascending aorta during open heart surgery interrupts coronary blood flow and provides a quiet, flaccid, bloodless heart, which facilitates the precise repair of intra-cardiac defects, expedites coronary anastomoses and minimizes the dangers of systematic air embolism. Nevertheless, severe myocardial damage may result as a consequence of the ischemic arrest process unless specific protective measures are utilized. [1,2] The extent of the injury is dependent on (1) the relationship between the myocardial energy demands during the ischemic period and the energy stores that are available to sustain critical metabolic needs; (2) mechanical injury that may occur as a consequence of the operative process, e.g. suture trauma, retraction injury, etc.; (3) injury as a consequence of the protective measures, e.g. cold, microvasculature rupture, etc. and (4) damage related to the reperfusion process.

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Authors
  1. Sidney Levitsky
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  2. Norman A. Silverman
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  3. Fang Jungpao
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  4. Harold Feinberg
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Editor information

Editors and Affiliations

  1. Beijing Heart, Lung and Blood Vessel Medical Center, Beijing, China

    Yingkai Wu MB. ChB. (Professor of Thoracic Surgery) (Professor of Thoracic Surgery)

  2. University of California at San Diego, California, USA

    Richard M. Peters M.D. (Professor of Surgery & Biomedical Engineering) (Professor of Surgery & Biomedical Engineering)

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© 1986 Science Press, Beijing and Martinus Nijhoff Publishers, Dordrecht

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Levitsky, S., Silverman, N.A., Jungpao, F., Feinberg, H. (1986). Cardioplegia. In: Wu, Y., Peters, R.M. (eds) International Practice in Cardiothoracic Surgery. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4259-2_18

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  • DOI: https://doi.org/10.1007/978-94-009-4259-2_18

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8391-1

  • Online ISBN: 978-94-009-4259-2

  • eBook Packages: Springer Book Archive

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