Abstract
Rheological and biophysical processes of aggregation or platelet adhesion can be diagramatically divided in 3 more or less simultaneous phases (1):
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a)
Transport of cells towards the vascular wall or towards other cells.
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b)
Activation phase: cell activation is achieved by aggregating agents released by platelets or other blood-cells (mainly erythrocytes). This primarily biochemical phase may also be related to flow and rheological parameters (rheological activation).
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c)
Adhesion, aggregation phase and platelet deposits: from a kinetic point of view, there is no doubt that the slowest process determines the overall rate of the whole process.
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© 1984 Martinus Nijhoff Publishers, The Hague
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Voisin, P., Larcan, A., Stoltz, J.F. (1984). Hemorheology and Platelet Activation: Theoretical and Experimental Aspects. In: Hardeman, M.R., Najean, Y. (eds) Blood cells in nuclear medicine, part I. Developments in Nuclear Medicine, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6027-5_26
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DOI: https://doi.org/10.1007/978-94-009-6027-5_26
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