Abstract
In the late 1970s and early 1980s there were several reports of a fatal diarrhoea of weaned rabbits (1–6). The features of the disease were the demonstration in the caeca of dead animals of a neutralizable iota-like toxin but the absence of detectable Clostridium perfringens Type E, which is known to produce iota toxin. It is now known that the causal organism is C. spiroforme (7–9). In the light of current knowledge, samples from all but one of the earlier outbreaks have been retrospectively analyzed and shown to contain C. spiroforme and its toxin. The condition, previously known as iota enterotoxaemia, can now be better termed C. spiroforme mediated diarrhoea (SMD).
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© 1984 Martinus Nijhoff Publishers, Dordrecht
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Carman, R.J., Borriello, S.P. (1984). Animal Models of Clostridium Spiroforme Mediated Diarrhoea (Iota Enterotoxaemia) of Rabbits. In: Hill, M.J. (eds) Models of Anaerobic Infection. New Perspectives in Clinical Microbiology, vol 10. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6054-1_7
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DOI: https://doi.org/10.1007/978-94-009-6054-1_7
Publisher Name: Springer, Dordrecht
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