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Non-invasive measurement of the concentration of melanin, xanthophyll, and hemoglobin in single fundus layers in vivo by fundus reflectometry

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Laser Scanning: Update 1

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Abstract

A new model of the reflection of the human ocular fundus on the basis of the adding-doubling method, an approximate solution of the radiative transport equation, is described. This model enables the calculation of the concentration of xanthophyll in the retina, of melanin in the retinal pigment epithelium and in the choroid, and of hemoglobin in the choroid from fundus reflectance spectra. The concentration values found in 12 healthy subjects are in excellent agreement with literature data. In single cases of pathologic fundus alterations possible benefits to the ophthalmologic diagnostics is demonstrated.

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Authors and Affiliations

  1. Department of Ophthalmology, University of Jena, Jena, Germany

    Martin Hammer, Dietrich Schweitzer, Eike Thamm & Achim Kolb

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  1. Martin Hammer
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  2. Dietrich Schweitzer
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  3. Eike Thamm
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  4. Achim Kolb
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Editors and Affiliations

  1. Parana 1239-1 Piso, 1018, Buenos Aires, Argentina

    Juan R. Sampaolesi

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© 2001 Springer Science+Business Media Dordrecht

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Hammer, M., Schweitzer, D., Thamm, E., Kolb, A. (2001). Non-invasive measurement of the concentration of melanin, xanthophyll, and hemoglobin in single fundus layers in vivo by fundus reflectometry. In: Sampaolesi, J.R. (eds) Laser Scanning: Update 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0322-3_18

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  • DOI: https://doi.org/10.1007/978-94-010-0322-3_18

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-3866-9

  • Online ISBN: 978-94-010-0322-3

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