Abstract
The circulation of blood through the vascular system is maintained by the rhythmic contraction of the heart. This pumping action depends on the ability of its muscular fibres to develop force and to shorten. An important development in our understanding of cardiac physiology has been the consideration of the heart as a muscle in order to gain greater insight into the operation of the heart as a pump.
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References
Henderson, A. H., Forman, R., Brutsaert, D. L. & Sonnenblick, E. H., Tetanic contraction in mamalian cardiac muscle. Cardiovasc. Res. Suppl. 1, 96–100 (1971).
Brady, A. J., Time and displacement dependence of cardiac contractility: problems in defining the active state and force-velocity relations. Fed. Proc. 24, 1410–1420 (1965).
Sonnenblick, E. H., Active state in heart muscle: its delayed onset and modification by inotropic agents. J. gen. Physiol. 50,661–676 (1967).
Edman, K. A. P. & Nilsson, E., Mechanical parameters of myocardial contraction studies at a constant length of the contractile element.Acta physiol. scand. 72,205–219, (1968).
Noble, M. I. M., Bowen, T. E. & Hefner, L. L., Force-velocity relationship of cat cardiac muscle, studied by isotonic and quick-release technique. Circulat. Res. 24,821–833, (1969).
Brady, A. J., Are force and velocity parameters of cardiac contractility separable? (Abstract). Cardiovasc. Res. (Abstracts of the VI World Congress of Cardiology) p. 36. London 1970.
Brutsaert, D. L., Claes, V. A. & Sonnenblick, E. H., Effects of abrupt load alterations on force-velocity-length and time relations during isotonic contractions of heart muscle: load clamping. J. Physiol. (Lond.) 216,319–330 (1970).
Ramsey, R. W. & Street, S. F., Isometric length-tension diagram of isolated skeletal muscle fibers of the frog. J. cell. comp. Physiol. 15,11–34 (1940).
Gordon, A. ML, Huxley, A. F. & Julian, F. J., The variation in isometric tension with sarcomere length in vertebrate muscle fibers. J. Physiol (Lond.). 184, 170–192 (1966).
Huxley, H. E., The mechanism of muscular contraction. Science 164,1356–1366 (1966).
Rüdel, R. & Taylor, S. R., Striated muscle fibers: facilitation of contraction at short lengths by caffeine.Science 172, 387–388 (1971).
Taylor, S. R. & Rüdel, R., Striated muscle fibers: Inactivation of contraction induced by shortening. Science 167, 882–884 (1970).
Huxley, A. F., Muscle structure and theories of contraction. Prog. Biophys. 7, 255–318 (1957).
Brutsaert, D. L., Claes, V. A. & Sonnenblick, E. H., Velocity of shortening of unloaded heart muscle and the length-tension relation. Circulat. Res. 29, 63–75 (1971).
Civan, M. M. & Podolsky, R. J., Contraction kinetics of striated muscle fibres following quick changes in load. J. Physiol (Lond.). 184,511–534 (1966).
Armstrong, C. F., Huxley, A. F. & Julian, F. J., Oscillatory responses in frog skeletal muscle fibers. J. Physiol (Lond.). 186, 26–27 P (1966).
Brutsaert, D. L., Vergelijkende studie over de dubbele stimulatie-potentiering, de post- extrasystolische potentiering en de frequentiepotentiering van de contractiliteit van het hart. Aggregation thesis. Gent 1967.
Brutsaert, D. L., Parmley, W. W. & Sonnenblick, E. H., Effects of various inotropic interventions on the dynamic properties of the contractile elements in heart muscle of the cat. Circulât. Res. 27, 513–522 (1970).
Brutsaert, D. L. & Sonnenblick, E. H., Nature of the force-velocity relation in heart muscle. Cardiovasc. Res. Suppl. 1,18–33 (1971).
Sonnenblick, E. H., Implications of muscle mechanics in the heart. Fed. Proc. 21 974–990 (1962).
Katz, A. M., Contractile proteins of the heart. Physiol Rev. 50, 63–158 (1970).
Ebashi, S. & Endo, M., Calcium ion and muscle contraction. In: Butler, J. A. V. & Noble, D. (eds.), Progress in biophysics and molecular biology, pp. 123–183. Oxford 1968.
Brutsaert, D. L., Claes, V. A. and Goethals, M., Effect of calcium on force-velocity- length relations of heart muscle of the cat. Submitted for publication 1972.
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© 1971 Leiden University Press, Leiden, The Netherlands
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Brutsaert, D.L. (1971). The Significance of Measurement of Contractility of the Heart. In: Snellen, H.A., Hemker, H.C., Hugenholtz, P.G., Van Bemmel, J.H. (eds) Quantitation in Cardiology. Boerhaave Series for Postgraduate Medical Education, vol 8. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-2927-8_14
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DOI: https://doi.org/10.1007/978-94-010-2927-8_14
Publisher Name: Springer, Dordrecht
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