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Calcium Antagonists, Hypertension, and Atherosclerosis

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Calcium Antagonists

Part of the book series: Medical Science Symposia Series ((MSSS,volume 3))

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Abstract

Calcium antagonists are now a well-established class of drugs in widespread clinical use. They comprise a large variety of chemical structures in which several subclasses have been identified: the dihydropiridines, with nifedipine as the classical reference compound and lacidipine as a drug representing the latest generation of calcium antagonists; the phenylalkylamines, represented by verapamil; the benzothiazepines, with diltiazem, and a small group represented by compounds like bepridil and flunarizine.

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References

  1. Fleckenstein A. (1983): Calcium Antagonism in Heart and Smooth Muscle. John Wiley & Sons, New York.

    Google Scholar 

  2. Zanchetti A. (1987): Am. J. Card., 59: 130B-136B.

    Article  Google Scholar 

  3. MacMahon S.W., Cutler J.A., Furberg C.D. and Payne G.H. (1986): Prog. Cardiovasc. Dis., 29(suppl.1): 99–118.

    Article  PubMed  CAS  Google Scholar 

  4. Strandgaard S. and Haunso S. (1987): Lancet, 2: 658–660.

    Article  PubMed  CAS  Google Scholar 

  5. Welin L., Svardsudd K., Wilhemsen L., Larsson B. and Tibblin G. (1987): New Engl. J. Med., 317: 521–526.

    Article  PubMed  CAS  Google Scholar 

  6. Ross R.R. (1986): New Engl. Med., 314: 488–500.

    Article  CAS  Google Scholar 

  7. Murno J.M. and Cotran R.S. (1988): Laboratory Invest., 58: 249–261.

    Google Scholar 

  8. Kiowski W., Eme P. and Büiler F.R. (1989): Clin. Exp. Hyper. Theory and Practice, A11(5–6): 1085–1096.

    Article  CAS  Google Scholar 

  9. Parmley W.W., Blumlein S. and Sievers R. (1985): Am. J. Cardiol., 55: 165B-171B.

    Article  Google Scholar 

  10. Weinstein D.B. (1988): J. Cardiovasc. Pharmacol., 12(suppl.6): S29-S35.

    Article  Google Scholar 

  11. Kramsc D.M., Aspen A.J. and Rotzler L.J. (1981): Science, 213: 1511–1512.

    Article  Google Scholar 

  12. Mutoh S., Nomoto A., Sekiguchi C. and Yamaguchi I. (1988): Atherosclerosis, 73: 181–189.

    Article  PubMed  CAS  Google Scholar 

  13. Kolbuchi Y., Sakai S., Miura S., Ono T., Shibayama F. and Ohtsuka M. (1989): Atherosclerosis, 79: 147–155.

    Article  Google Scholar 

  14. Kjieldsen K. and Stender S. (1989): Proc. Soc. Exp. Biol. Med., 190: 219–228.

    Google Scholar 

  15. Nomoto A., Mutoh S., Hagihara H. and Yamaguchi I. (1988): Atherosclerosis, 72: 213–219.

    Article  PubMed  CAS  Google Scholar 

  16. Jackson C.L., Raymond C.B. and Bowyer D. (1989): Atherosclerosis, 80: 17–26.

    Article  PubMed  CAS  Google Scholar 

  17. Betz E. (1988): Ann. N.Y. Acad. Sci., 522: 399–410.

    Article  PubMed  CAS  Google Scholar 

  18. Micheli D., Ratti E., Toson G. and Gaviraghi G. (1991): J. Cardiovasc. Pharmacol., 17(suppl.4): S1-S8.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Glaxo Research Laboratories, Via A. Fleming 4, 37100, Verona, Italy

    C. Carpi

Authors
  1. C. Carpi
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Editor information

Editors and Affiliations

  1. Laboratory of Pharmacology, Catholic University of Louvain, Brussels, Belgium

    T. Godfraind

  2. Institute of Pharmacological Sciences, University of Milan, Milan, Italy

    R. Paoletti  & S. Govoni  & 

  3. Center for Experimental Therapeutics, Baylor Institute of Medicine, Houston, Texas, USA

    P. M. Vanhoutte

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© 1993 Springer Science+Business Media Dordrecht

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Carpi, C. (1993). Calcium Antagonists, Hypertension, and Atherosclerosis. In: Godfraind, T., Paoletti, R., Govoni, S., Vanhoutte, P.M. (eds) Calcium Antagonists. Medical Science Symposia Series, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-1725-8_25

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  • DOI: https://doi.org/10.1007/978-94-011-1725-8_25

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4756-2

  • Online ISBN: 978-94-011-1725-8

  • eBook Packages: Springer Book Archive

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