Abstract
It is well known that a number of radiopharmaceuticals show a non specific uptake in inflammatory processes. Whilst this may be of some diagnostic value there is a need for reagents which localise specifically in foci of inflammation and which distinguish between infection and aseptic inflammatory processes not to mention occult foci of infection and non specific tumour uptake. Such a requirement immediately introduces the concept that different classes of radiopharmaceutical will be required to distinguish these types of lesion from one another. Inflammatory foci do not have a specific receptor to which a potential radiopharmaceutical can be targeted but whilst the inflammatory process is a complicated phenomenon it does have a number of features which can positively influence the accumulation of radiopharmaceuticals in the lesion.
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Cox, P.H. (1998). Radiopharmaceuticals for Imaging Infectious and Inflammatory Foci. In: Cox, P.H., Buscombe, J.R. (eds) The Imaging of Infection and Inflammation. Developments in Nuclear Medicine, vol 31. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-4990-7_2
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DOI: https://doi.org/10.1007/978-94-011-4990-7_2
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