Abstract
The success of liposomes in the therapy of experimental models for visceral leishmaniasis has been demonstrated recently in several laboratories (Alving et al. 1978, Black et al. 1977, New et al. 1978), and may be attributed to the fact that both liposomes and the leishmanial parasite are taken up from the bloodstream by the Kupffer cells of the liver, so that a high concentration of liposomallyentrapped drug is brought into close contact with the parasite.
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References
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© 1982 C.G. Wilson, J.G. Hardy, M. Frier and S.S. Davis
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New, R.R.C., Chance, M.L., Critchley, M. (1982). The Distribution of Radiolabelled Drug in Animals Infected with Cutaneous Leishmaniasis: Comparison of Free and Liposome-Bound Sodium Stibogluconate. In: Wilson, C.G., Hardy, J.G., Frier, M., Davis, S.S. (eds) Radionuclide Imaging in Drug Research. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-9728-1_18
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DOI: https://doi.org/10.1007/978-94-011-9728-1_18
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