Abstract
Many plants have long been used as traditional herbal medicines, and several pharmacological activities have been observed in pectic polysaccharides from medicinal plants. To resolve the biological functions of bioactive pectins and pectic polysaccharides for health care, studies on carbohydrate sequences having pharmacological activities and their modes of actions are required. Present paper describes recent studies on a murine B cell proliferating pectin from Bupleurum falcatum, murine intestinal immune system enhancing pectic polysaccharides from Atractylodes lancea, and human natural antibody for pectic polysaccharides.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Guo, Y-J., Matsumoto, T., Kikuchi, Y., Ikejima, T., Wang, B-X. and Yamada, H. (2000) Effects of a pectic polysaccharide from a medicinal herb, the roots of Bupleurum falcatum L. on interleukin 6 production of murine B cells and B cell line, Immunopharmacol., 49, 307–316.
Hirano, M., Kiyohara, H., Matsumoto, T. and Yamada, H. (1994) Structural studies of endopolygalacturonase-resistant fragments in anti-ulcer pectin from the roots of Bupleurum falcatum L., Carbohydr. Res., 251, 145–162.
Hong, T., Matsumoto, T., Kiyohara, H. and Yamada, H. (1998) Enhanced production of hematopoietic growth factors through T cell activation in Peyer’s patches by oral administration of Kampo (Japanese herbas) medicines, *Juzen-taiho-to’, Phytomedicine, 5,353–360.
Ishii, T. and Matsunaga, T (1996) Isolation and characterization of a boron-rhamnogalacturonan-II complex from cell walls of sugar beet pulp, Carbohydr. Res., 284,1–9.
Kaneko, S., Ishi, T. and Matsunaga, T. (1997) A boron-rhamnogalacturonan-II complex from bamboo shoot cell walls, Phytochem., 44,243–248.
Kobayashi, M., Matoh, T. and Azuma, J. (1996) Two chains of rhamnogalacturonan II are cross-linked by borate-diol ester bonds in higher plant cell walls. Plant Physiol., 110, 1017–1020.
Langhout, D. J., Schutte, J. B., Van Leeuwen, P., Wiebenga, J. and Tamminga S. (1999) Effect of dietary high- and low-methylated citrus pectin on the activity of the ileal microflora and morphology of the small intestinal wall of broiler chicks, British Poultry Sei., 40,340–347.
Lim, B. O., Yamada, K., Nonaka, M., Kuramoto, Y., Hung, P. and Sugano, M. (1997) Dietary fibers modulate indices of intestinal immune function in rats, J. Nutr., 127, 663–667.
Mandai, M., Olson, D. J., Sharma, T., Vadlamudi, R. K. and Kumar, R. (2001) Butyric acid induces apoptosis by upregulating Bax expression via stimulation of the c-Jun N-terminal kinase/activation protein-1 pathway in human colon cancer cells, Gastroenterology, 120, 71–78.
O’Neill, M. A., Warrenfeltz, D., Kates, K., Pellerin, P., Doco, T., Darvill, A. G. and Albersheim, P. (1996) Rhamnogalacturonan-II, a pectic polysaccharide in the walls of growing plant cell, forms a dimer that is covalently cross-linked by a borate ester. In vitro conditions for the formation and hydrolysis of the dimer., J. Biol. Chem., 271, 22923–22930.
Sakurai, M. H., Matsumoto, T., Kiyohara, H. and Yamada, H. (1996) Detection and tissue distribution of antiulcer polysaccharides from Bupleurum falcatum L. by polyclonal antibody, Planta Med., 62, 341–346.
Sakurai, M. H., Kiyohara, H., Matsumoto, T., Tsumuraya, Y., Hashimoto, Y. and Yamada, H. (1998) Characterization of antigenic epitopes in anti-ulcer pectic polysaccharides from Bupleurum falcatum L, using several carbohydrases, Carbohydr. Res., 311,218–229.
Sakurai, M. H., Matsumoto, T., Kiyohara, H. and Yamada, H. (1999) B cell proliferation activity of pectic polysaccharide from a medicinal herb, the roots of Bupleurum falcatum L. and its structural requirement, Immunology, 97, 540–547.
Shin, K-S., Kiyohara, H., Matsumoto, T. and Yamada, H. (1997) Rhamnogalacturonan II from the leaves of Panax ginseng C. A. Meyer as a macrophage Fc receptor expression-enhancing polysaccharide, Carbohydr. Res., 300,239–249.
Shin, K-S., Kiyohara, H., Matsumoto, T. and Yamada, H. (1998) Rhamnogalacturonan II dimers cross-linked by borate diesters from the leaves of Panax ginseng C. A. Meyer are responsible for expression of their IL-6 production enhancing activities, Carbohydr. Res., 307,97–106.
Tappenden, K. A., Pratt, V. C, Goruk, S. D., Field, C. J. and McBurney, M. C. (1995) Short chain fatty acid (SCFA) supplementation of total parenteral nutrition (TPN) improves whole body response to intestinal resection, FASEB J. 9, 862A.
Yamada, H., Kiyohara H. and Otsuka, Y. (1987) Further structural studies of an anti-complementary acidic heteroglycan from the leaves of Artemisiaprinceps, Carbohydr. Res., 170, 181–191.
Yamada, H., Nagai, T., Cyong J-C. and Otsuka, Y. (1991) Mode of complement activation by acidic heteroglycans from the leaves of Artemisia princeps PAMP, Chem. Pharm. Bull., 39,2077–2081.
Yamada, H., (1994) Pectic polysaccharides from Chinese herbs: Structure and biological activity, Carbohydr. Polymers, 25,269–276.
Yamada, H., (1996) Contribution of pectins on health care, in J. Visser and A.G.J. Voragen (eds) Pectin and Pectinase, Progress in Biotechnology, Elsevier, Amsterdam., Vol. 4, pp. 173–190.
Yamada, H. and Kiyohara, H. (1999) Complement activating polysaccharides from medicinal herbs, in H. Wagner (eds), Immunomodulatory Agents from Plants, Birkhäuser Publishing Ltd., Basel., pp. 161–202.
Yu, K-W., Kiyohara, H., Matsumoto, T., Yang, H-C. and Yamada, H. (1998) Intestinal immune system modulating polysaccharides from rhizomes of Atractylodes lancea, Planta Med., 64, 714–719.
Yu, K.-W., Kiyohara, H., Matsumoto, T., Yang, H.-C. and Yamada, H. (2001a) Structural characterization of intestinal immune system modulating new arabino-3, 6-galactan from rhizomes of Atractylodes lancea DC, Carbohydr. Polymer, 46, 147–156.
Yu, K.-W., Kiyohara, H., Matsumoto, T., Yang, H.-C. and Yamada, H. (2001b) Characterization of pectic polysaccharides having intestinal immune system modulating activity from rhizomes of Atractylodes lancea DC, Carbohydr. Polymer, 46, 125–134.
Zhao, J-F, Kiyohara, H, Yamada, H, Takemoto N. and Kawamura, H. (1991) Heterogeneity and characterization of mitogenic and anti-complementary pectic polysaccharides from the roots of Glycyrrhiza uralensis Fisch, et DC,Carbohydr. Res, 219, 149–172.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2003 Springer Science+Business Media Dordrecht
About this chapter
Cite this chapter
Yamada, H., Kiyohara, H., Matsumoto, T. (2003). Recent Studies on Possible Functions of Bioactive Pectins and Pectic Polysaccharides from Medicinal Herbs on Health Care. In: Voragen, F., Schols, H., Visser, R. (eds) Advances in Pectin and Pectinase Research. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0331-4_35
Download citation
DOI: https://doi.org/10.1007/978-94-017-0331-4_35
Publisher Name: Springer, Dordrecht
Print ISBN: 978-90-481-6229-1
Online ISBN: 978-94-017-0331-4
eBook Packages: Springer Book Archive