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Brain Systems for the Pleasure of Food and Other Primary Rewards

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Anhedonia: A Comprehensive Handbook Volume I

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Abstract

The orbitofrontal cortex, anterior cingulate cortex, and amygdala are key components of the reward and pleasure systems of the human brain. Investigations with functional magnetic resonance imaging (fMRI) of how these brain systems respond to food and other primary, sensory rewards can reveal basic principles of their function in reward, experienced pleasure, decision-making, and behavior. Here I review recent advances that have been made with this approach, with the aim to characterize the functional specializations of the orbitofrontal cortex, anterior cingulate cortex and amygdala in reward, pleasure and decision-making. The specific aims are (i) to show that the orbitofrontal cortex, anterior cingulate cortex, and amygdala are principal structures in the human brain for reward and pleasure; (ii) to describe their roles in information processing for rewards; (iii) to outline some key principles according to which human reward and pleasure systems operate; (iv) to consider the relationship between these reward systems and the decision systems in the ventromedial prefrontal cortex; and (v) to illustrate with specific examples how this approach to reward and pleasure is also relevant to applied disciplines including food design, food marketing, health policy, and clinical conditions in which hedonic responses to rewards are altered.

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Acknowledgements

I am grateful to Edmund T. Rolls for collaboration on much of the work reviewed in this chapter. Many of the experiments described were performed in the Rolls laboratory at Oxford, and many of the theoretical concepts presented here were pioneered by Edmund Rolls or developed in collaboration with him. The writing of this chapter was supported by a Research Fellowship at Selwyn College, Cambridge.

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    Fabian Grabenhorst

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Grabenhorst, F. (2014). Brain Systems for the Pleasure of Food and Other Primary Rewards. In: Ritsner, M. (eds) Anhedonia: A Comprehensive Handbook Volume I. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-8591-4_8

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  • DOI: https://doi.org/10.1007/978-94-017-8591-4_8

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