Skip to main content
SpringerLink
Log in

Computer-Assisted Treatment Planning Approaches for IMRT

  • Chapter
  • First Online:
Image-Based Computer-Assisted Radiation Therapy

  • 1103 Accesses

Abstract

This chapter gives an overview about the computer aided for IMRT. It will be begun with the historical of the evolution in radiotherapy techniques and then continuously with the comparison between 3DCRT and IMRT techniques. This chapter discusses the terminology in IMRT and also its techniques that are already implemented in clinical cases. This chapter will be closed with discussion about the optimization criteria that are used in IMRT.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 139.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 179.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Alber M, Nüsslin F (2000) Intensity modulated photon beams subject to minimal surface smoothing constraint. Phys Med Biol 45(5):N49–N52

    Article  CAS  PubMed  Google Scholar 

  • Alber M, Nüsslin F (2001) Optimization of intensity modulated radiotherapy under constraints for static and dynamic MLC delivery. Phys Med Biol 46(12):3229–3239

    Article  CAS  PubMed  Google Scholar 

  • Bednarz G, Michalski D, Houser C, Huq MS, Xiao Y, Anne PR, Galvin J (2002) The use of mixed-integer programming for inverse treatment planning with pre-defined field segments. Phys Med Biol 47(13):2235–2245

    Article  PubMed  Google Scholar 

  • Blomgren H, Lax I, Naslund I, Svanstrom R (1995) Stereotactic high dose fraction radiation therapy of extracranial tumors using an accelerator. Clinical experience of the first thirty-one patients. Acta Oncol 34:861–870

    Article  CAS  PubMed  Google Scholar 

  • Bortfeld T, Boyer AL, Schlegel W, Kahler DL, Waldron TJ (1994a) Realization and verification of three-dimensional conformal radiotherapy with modulated fields. Int J Radiat Oncol Biol Phys 30(4):899–908

    Article  CAS  PubMed  Google Scholar 

  • Bortfeld T, Haler DL, Waldron TJ, Boyer AL (1994b) X-ray compensation with multileaf collimators. Int J Radiat Oncol Biol Phys 28:723–739

    Article  CAS  PubMed  Google Scholar 

  • Brahme A (1988) Optimisation of stationary and moving beam radiation therapy techniques. Radiother Oncol 12:129–140

    Article  CAS  PubMed  Google Scholar 

  • Brahme A (1993) Optimization of radiation therapy and the development of multileaf collimation. Int J Radiat Oncol Biol Phys 25(2):373–375

    Article  CAS  PubMed  Google Scholar 

  • Brahme A (1994) Optimization of radiation therapy. Int J Radiat Oncol Biol Phys 28(3):785–787

    Article  Google Scholar 

  • Brahme A, Roos JE, Lax I (1982) Solution of an integral equation encountered in rotation therapy. Phys Med Biol 27:1221–1229

    Article  CAS  PubMed  Google Scholar 

  • Budgell GJ, Mott JHL, Williams PC, Brown KJ (2000) Requirements for leaf position accuracy for dynamic multileaf collimation. Phys Med Biol 45:1211–1227

    Article  CAS  PubMed  Google Scholar 

  • Chen Y, Michalski D, Houser C, Galvin J (2002) A deterministic iterative least-squares algorithm for beam weight optimization in conformal radiotherapy. Phys Med Biol 47(10):1647–1658

    Article  PubMed  Google Scholar 

  • Cho PS, Marks RJ II (2000) Hardware-sensitive optimization for intensity modulated radiotherapy. Phys Med Biol 45:429–440

    Article  CAS  PubMed  Google Scholar 

  • Chui CS, LoSasso T, Spirou S (1994) Dose calculation for photon beams with intensity modulation generated by dynamic jaw or multileaf collimations. Med Phys 21:1237–1244

    Article  CAS  PubMed  Google Scholar 

  • Chui CS, Chan MF, Yorke E, Spirou S, Ling CC (2001) Delivery of intensity modulated radiation therapy with a conventional multileaf collimator: comparison of dynamic and segmental methods. Med Phys 28:2441–2449

    Article  CAS  PubMed  Google Scholar 

  • Convery DJ, Webb S (1998) Generation of discrete beam-intensity modulation by dynamic multileaf collimation under minimum leaf separation constraints. Phys Med Biol 43:2521–2538

    Article  CAS  PubMed  Google Scholar 

  • Cotrutz C, Lahanas M, Kappas C, Baltas D (2001) A multiobjective gradient-based dose optimization algorithm for external beam conformal radiotherapy. Phys Med Biol 46(8):2161–2175

    Article  CAS  PubMed  Google Scholar 

  • Crooks SM, McAven LF, Robinson DF, Xing L (2002) Minimizing delivery time and monitor units in static IMRT by leaf-sequencing. Phys Med Biol 47(17):3105–3116

    Article  CAS  PubMed  Google Scholar 

  • DeGersem W, Claus F, DeWagter C, DeNeve W (2001a) An anatomy-based beam segmentation tool for intensity modulated radiation therapy and its application to head and neck cancer. Int J Radiat Oncol Biol Phys 51(3):849–859

    Article  CAS  Google Scholar 

  • DeGersem W, Claus F, DeWagter C, VanDuyse B, DeNeve W (2001b) Leaf position optimization for step-and-shoot IMRT. Int J Radiat Oncol Biol Phys 51(5):1371–1388

    Article  CAS  Google Scholar 

  • DeNeve W, DeWagter C, DeJaeger K, Thienpont M, Colle C, Derycke S, Schelfhout J (1996) Planning and delivering high doses to targets surrounding the spinal cord at the lower neck and upper mediastinal levels: static beam-segmentation technique executed with a multileaf collimator. Radiother Oncol 40(3):271–279

    Article  CAS  Google Scholar 

  • Galvin JM, Chen XG, Smith RM (1993) Combining multileaf fields to modulate fluence distributions. Int J Radiat Oncol Biol Phys 27:697–705

    Article  CAS  PubMed  Google Scholar 

  • Gustafsson A, Lind BK, Brahme A (1994) A generalized pencil beam algorithm for optimization of radiation therapy. Med Phys 21(3):343–356

    Article  CAS  PubMed  Google Scholar 

  • Hamilton A, Lulu B, Fosmire H, Stea B, Cassady J (1995) Preliminary clinical experience with linear accelerator-based spinal stereotactic radiosurgery. Technique and application. Neurosurgery 36:311–319

    Article  CAS  PubMed  Google Scholar 

  • International Commission on Radiation Units and Measurements (ICRU) Report 50 (1993) Prescribing, recording, and reporting photon beam therapy. International Commission on Radiation Units and Measurements, Bethesda

    Google Scholar 

  • International Commission on Radiation Units and Measurements (ICRU) Report 83 (2010) Prescribing, recording, and reporting photon beam intensity modulated radiation therapy. International Commission on Radiation Units and Measurements, Bethesda

    Google Scholar 

  • Jaffray DA (2005) Emergent technologies for 3-dimensional image-guided radiation delivery. Semin Radiat Oncol 15:208–216

    Article  PubMed  Google Scholar 

  • John Schreiner L (2006) Dosimetry in modern radiation therapy: Limitations and needs. J Phys Conf Ser 56:1–13

    Article  Google Scholar 

  • Keller-Reichenbecher MA, Bortfeld T, Levegrun S, Stein J, Prieser K, Schlegel W (1999) Intensity modulation with the ‘step and shoot’ technique using a commercial MLC: a planning study. Multileaf collimator. Int J Radiat Oncol Biol Phys 45:1315–1324

    Article  CAS  PubMed  Google Scholar 

  • Kestin LL, Sharpe MB, Frazier RC, Vicini FA, Yan D, Matter RC, Martinez AA, Wong JW (2000) Intensity modulation to improve dose uniformity with tangential breast radiotherapy: initial clinical experience. Int J Radiat Oncol Biol Phys 48:1559–1568

    Article  CAS  PubMed  Google Scholar 

  • Langer M, Morrill S, Brown R, Lee O, Lane R (1996) A comparison of mixed integer programming and fast simulated annealing for optimizing beam weights in radiation therapy. Med Phys 23:957–964

    Article  CAS  PubMed  Google Scholar 

  • Langer M, Thai V, Papiez L (2001) Improved leaf sequencing reduces segments or monitor units needed to deliver IMRT using multileaf collimators. Med Phys 28(12):2450–2458

    Article  CAS  PubMed  Google Scholar 

  • LoSasso T, Chui C-S, Ling CC (1998) Physical and dosimetric aspects of a multileaf collimation system used in the dynamic mode for implementing intensity modulated radiotherapy. Med Phys 25:1919–1927

    Article  CAS  PubMed  Google Scholar 

  • Mackie R, Deasy J, Holmes T, Fowler J (1994) Optimization of radiation therapy and the development of multileaf collimation. Int J Radiat Oncol Biol Phys 28(3):784–785

    Article  CAS  PubMed  Google Scholar 

  • Mohan R, Ling CC (1995) When becometh less more? Int J Radiat Oncol Biol Phys 33:235–237

    Article  CAS  PubMed  Google Scholar 

  • Mohan R, Wang XH (1996) Physical vs. biological objectives for treatment plan optimization. Radiother Oncol 40:186–187

    Article  Google Scholar 

  • Niemierko A (1992) Random search algorithm (RONSC) for the optimization of radiation therapy with both physical and biological endpoints and constraints. Int J Radiat Oncol Biol Phys 23:89–98

    Article  CAS  PubMed  Google Scholar 

  • Niemierko A (1999) A generalized concept of equivalent uniform dose (EUD). Med Phys 26(6):1100

    Google Scholar 

  • Remouchamps VM, Vicini FA, Sharpe MB, Kestin LL, Martinez AA, Wong JW (2003) Significant reductions in heart and lung doses using deep inspiration breath hold with active breathing control and intensity-modulated radiation therapy for patients treated with locoregional breast irradiation. Int J Radiat Oncol Biol Phys 55(2):392–406

    Article  PubMed  Google Scholar 

  • Saw CB, Siochi RC, Ayyangar KM, Zhen W, Enke CA (2001) Leaf sequencing techniques for MLC-based IMRT. Med Dosim 26(2):199–204

    Article  CAS  PubMed  Google Scholar 

  • Schlegel W, Mahr A (2001) 3D conformal radiation therapy: multimedia introduction to methods and techniques. Springer, Heidelberg (e-book)

    Google Scholar 

  • Shepard DM, Earl MA, Li XA, Naqvi S, Yu C (2002) Direct aperture optimization: a turnkey solution for step-and-shoot IMRT. Med Phys 29(6):1007–1018

    Article  CAS  PubMed  Google Scholar 

  • Söderström S, Brahme A (1995) What is the most suitable number of photon beam portals in coplanar radiation therapy. Int J Radiat Oncol Biol Phys 33:151–159

    Article  PubMed  Google Scholar 

  • Söderström S, Brahme A (1996) Small is beautiful-and often enough. Int J Radiat Oncol Biol Phys 34(3):757–758

    Article  PubMed  Google Scholar 

  • Spirou SV, Chui C-S (1998) A gradient inverse planning algorithm with dose-volume constraints. Med Phys 25:321–333

    Article  CAS  PubMed  Google Scholar 

  • Spirou SV, Fournier-Bidoz N, Yang J, Chui CS, Ling CC (2001) Smoothing intensity-modulated beam profiles to improve the efficiency of delivery. Med Phys 28:2105–2112

    Article  CAS  PubMed  Google Scholar 

  • Stein J, Mohan R, Wang XH, Bortfeld T, Wu Q, Preiser K, Ling CC, Schlegel W (1997) Number and orientation of beams in intensity-modulated radiation treatments. Med Phys 24(2):149–160

    Article  CAS  PubMed  Google Scholar 

  • Sternick ES (ed) (1997) The theory and practice of intensity modulated radiation therapy. Advanced Medical Publishing, Madison

    Google Scholar 

  • St-Hilaire J, Sévigny C, Beaulieu F, Gingras L, Tremblay D, Beaulieu L (2009) Optimization of photon beam energy in aperture-based inverse planning. J Appl Clin Med Phys 10(4):36–54

    Article  Google Scholar 

  • Storchi PRM, van Battum LJ, Woudsrta E (1999) Calculation of a pencil beam kernel from measured photon beam data. Phys Med Biol 44:2917–2928

    Article  CAS  PubMed  Google Scholar 

  • van Santvoort JPC, Heijmen BJM (1996) Dynamic multileaf collimation without ‘tongue and groove’ underdosage effects. Phys Med Biol 41:2091–2105

    Article  PubMed  Google Scholar 

  • Wang XH, Mohan R, Jackson A, Leibel SA, Fuks Z, Ling CC (1995) Optimization of intensity-modulated 3D conformal treatment plans based on biological indices. Radiother Oncol 37:140–152

    Article  CAS  PubMed  Google Scholar 

  • Webb S (1992) Optimisation by simulated annealing of three-dimensional, conformal treatment planning for radiation fields defined by a multileaf collimator: 2. Inclusion of two-dimensional modulation of the x-ray intensity. Phys Med Biol 37:1689–1704

    Article  CAS  PubMed  Google Scholar 

  • Webb S (1994) Optimizing the planning of intensity-modulated radiotherapy. Phys Med Biol 39(12):2229–2246

    Article  CAS  PubMed  Google Scholar 

  • Webb S (1998a) Configuration options for intensity-modulated radiation therapy using multiple static fields shaped by a multileaf collimator. II: constraints and limitations on 2D modulation. Phys Med Biol 43(6):1481–1495

    Article  CAS  PubMed  Google Scholar 

  • Webb S (1998b) Configuration options for intensity-modulated radiation therapy using multiple static fields shaped by a multileaf collimator. Phys Med Biol 43(2):241–260

    Article  CAS  PubMed  Google Scholar 

  • Webb S (2000) Advances in three-dimensional conformal radiation therapy physics with intensity modulation. Lancet Oncol 1:30–36

    Article  CAS  PubMed  Google Scholar 

  • Webb S (2005) Contemporary IMRT: developing physics and clinical implementation. Institute of Physics Publishing, Bristol/Philadelphia

    Google Scholar 

  • Webb S, Bortfeld T, Stein J, Convery D (1997) The effect of stair-step leaf transmission on the ‘tongue-and-groove problem’ in dynamic radiotherapy with multileaf collimator. Phys Med Biol 42:595–602

    Article  CAS  PubMed  Google Scholar 

  • Xia P, Verhey LJ (1998) Multileaf collimator leaf sequencing algorithm for intensity modulated beams with multiple static segments. Med Phys 25:1424–1434

    Article  CAS  PubMed  Google Scholar 

  • Xiao Y, Galvin J, Hossain M, Valenti R (2000) An optimized forward-planning technique for intensity modulated radiation therapy. Med Phys 9:2093–2099

    Article  Google Scholar 

  • Xiao Y, Censor Y, Michalski D, Galvin J (2003) The least-intensity feasible solution for aperture-based inverse planning in radiation therapy. Ann Oper Res 119:183–203

    Article  Google Scholar 

  • Yu CX (1995) Intensity-modulated arc therapy with dynamic multileaf collimation – an alternative to tomotherapy. Phys Med Biol 40(9):1435–1449

    Article  CAS  PubMed  Google Scholar 

  • Yu CX, Shepard D, Earl M, Cao D, Luan S, Wang C, Chen DZ (2006) New developments in intensity modulated radiation therapy. Technol Cancer Res Treat 5(5):451–464

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physics, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Bandung, Indonesia

    Freddy Haryanto

Authors
  1. Freddy Haryanto
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Freddy Haryanto .

Editor information

Editors and Affiliations

  1. Department of Health Sciences, Kyushu University, Fukuoka, Japan

    Hidetaka Arimura

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer Nature Singapore Pte Ltd.

About this chapter

Cite this chapter

Haryanto, F. (2017). Computer-Assisted Treatment Planning Approaches for IMRT. In: Arimura, H. (eds) Image-Based Computer-Assisted Radiation Therapy. Springer, Singapore. https://doi.org/10.1007/978-981-10-2945-5_8

Download citation

  • DOI: https://doi.org/10.1007/978-981-10-2945-5_8

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-2943-1

  • Online ISBN: 978-981-10-2945-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation