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Complications and Other Conditions in Refractory Status Epilepticus That Require Attention

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Refractory Status Epilepticus

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Abstract

Refractory status epilepticus (RSE) is one of the most common diseases seen in neurological intensive care and is associated with a high mortality rate. Complications in epilepsy, including fever, acidosis, blood pressure disorders, and brain edema, are often directly implicated in the death of affected patients. They are therefore key factors that contribute to the failure of antiepileptic treatments. In this chapter, we focus on rare complications in RSE. These include hyponatremia and rhabdomyolysis as well as other conditions that require attention, such as malnutrition, in patients with status epilepticus (SE), status epilepticus caused by alcohol withdrawal syndrome (AWS), and sudden unexpected death in epilepsy (SUDEP). We explore the underlying pathogenesis and treatments for these conditions and describe the measures used to control their relevant complications with the aim of reducing mortality and greatly improving the survival rate and quality of life of affected patients.

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  1. Department of Neurology, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, 107 Wenhuaxi Road, Jinan, Shandong, 250012, China

    Shengnian Zhou

  2. Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, Ouhai District, Wenzhou City, Zhejiang Province, 325015, China

    Xinshi Wang Ph.D.

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    Xuefeng Wang

  2. Institute on Global Health (IGH), Peking University & UN Consultative Committee on Life Science and Human Health (CCLH), Beijing, China

    Shichuo Li

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Zhou, S., Wang, X. (2017). Complications and Other Conditions in Refractory Status Epilepticus That Require Attention. In: Wang, X., Li, S. (eds) Refractory Status Epilepticus. Springer, Singapore. https://doi.org/10.1007/978-981-10-5125-8_9

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