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Polymeric Gels: Vehicles for Enhanced Drug Delivery Across Skin

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Polymer Gels

Part of the book series: Gels Horizons: From Science to Smart Materials ((GHFSSM))

Abstract

Polymeric gels have emerged as promising vehicles for drug delivery across the skin. Stratum corneum, the topmost layer of the skin, does not allow hydrophilic and high molecular weight drugs to permeate without enhancing techniques. A number of enhancement techniques are being developed to increase the transdermal drug permeation. The transdermal route has many advantages and has therefore evolved as an attractive and convenient alternative to the existing routes of drug delivery that causes many side effects. In the present chapter, we shall be focusing on the physical enhancement techniques of iontophoresis, electroporation and sonophoresis for transport of drug molecules across skin using polymeric gels.

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  1. Centre for Biomedical Engineering, Indian Institute of Technology, New Delhi, India

    Rachna Prasad

  2. Biomedical Engineering Unit, All India Institute of Medical Sciences, New Delhi, India

    Veena Koul

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  1. Faculty in Manufacturing, Enhanced Composites and Structures Centre, School of Aerospace, Transport and Manufacturing, Cranfield University, Cranfield, United Kingdom

    Vijay Kumar Thakur

  2. Division of Chemistry, Government Degree College Bhoranj, Himachal Pradesh University, Shimla, Himachal Pradesh, India

    Manju Kumari Thakur

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Prasad, R., Koul, V. (2018). Polymeric Gels: Vehicles for Enhanced Drug Delivery Across Skin. In: Thakur, V., Thakur, M. (eds) Polymer Gels. Gels Horizons: From Science to Smart Materials. Springer, Singapore. https://doi.org/10.1007/978-981-10-6086-1_9

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