Abstract
Phycobiliproteins (PBPs) have widespread biotechnological applications including nutraceuticals, pharmaceuticals, food industry, cosmetics, agriculture, bioremediation, aquaculture, biofuels, and bioenergy. PC is water-soluble, brilliantly blue colored, and most widely used as natural fluorescent and pharmaceutical agents in various biotechnological applications. However, PE and APC are mainly used for fluorescent, cosmetics, and certain other biotechnological applications. Although numerous applications have been found on commercial production of PBPs from various cyanobacteria species, however, certain cyanobacterium like Spirulina sp. (Arthrospira) is much exploited for large-scale production. To enhance the diversity of PBP-based bioproduct, biotechnological companies of leading country have followed a wide range of extraction and purification technology to obtain higher product quality. Thus, modern research and development about novel structural configuration biliproteins have expanded the further application of PBPs in many therapeutic sciences. PC also acts as natural photosensitizer that is used for light-oriented therapy for tumor cells called as photodynamic therapy. PBP-based drugs are still in progress for use in various clinical applications. In this chapter, we have focused on therapeutic significance and probable mechanism of action of PBPs in various human diseases.
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Kannaujiya, V.K., Sundaram, S., Sinha, R.P. (2017). Role in Therapeutic Sciences. In: Phycobiliproteins: Recent Developments and Future Applications. Springer, Singapore. https://doi.org/10.1007/978-981-10-6460-9_9
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