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Daphnetin

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Natural Small Molecule Drugs from Plants

Abstract

Daphnetin is mainly extracted from Yu Ruixiang Changbai Daphne. Daphnetin has the pharmacological effects on cardiovascular system, central nervous system, and immune system, which made it mainly used for treatment of coronary heart disease, occlusive vascular disease, and Buerger’s disease in clinical. In the 1970s, the artificial synthesis of daphnetin, which promoted R&D, makes it a landmark of new drug discovery in China. Daphnetin has extensive pharmacological effects, but pharmacological researches are still based on animal experiments. Pharmacodynamics, pharmacokinetics, and clinical research for other indications are needed as soon as possible.

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Correspondence to Guan-Hua Du .

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© 2018 Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China

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Sun, L., Zhao, R., Yang, XY., Du, GH. (2018). Daphnetin. In: Natural Small Molecule Drugs from Plants. Springer, Singapore. https://doi.org/10.1007/978-981-10-8022-7_6

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